For procurement professionals, R&D scientists, and product formulators in the chemical and pharmaceutical industries, the consistent sourcing of high-quality intermediates is a cornerstone of operational success. 6-Methylnicotinic Acid (CAS 3222-47-7) is one such compound, vital for numerous synthesis processes. This guide aims to equip buyers with the knowledge needed to effectively source this critical chemical.

Understanding 6-Methylnicotinic Acid's Value Proposition

6-Methylnicotinic Acid is primarily recognized for its role as a key intermediate in the synthesis of the pharmaceutical Etoricoxib, a selective COX-2 inhibitor. This application alone drives significant demand, as pharmaceutical companies require consistent, high-purity material to meet stringent regulatory standards for drug manufacturing. Beyond pharmaceuticals, its utility extends to general organic synthesis, making it a valuable component for researchers developing new chemical entities and materials. For buyers, understanding these diverse applications helps in forecasting demand and specifying product requirements.

Key Considerations When Buying 6-Methylnicotinic Acid

When looking to buy 6-Methylnicotinic Acid, several factors are paramount:

• Purity: The most critical specification is purity. For pharmaceutical applications, a purity of ≥99% is often non-negotiable. This ensures minimal side reactions and optimal yield in subsequent synthesis steps. Always request a Certificate of Analysis (CoA) that clearly states the purity level and the analytical methods used.
• Supplier Reliability: Establishing a relationship with a dependable manufacturer or supplier is crucial. Consider factors like production capacity, lead times, track record, and their ability to consistently deliver without interruptions. A reliable supplier in China, for instance, can offer competitive pricing and a robust supply chain.
• Product Specifications: Beyond purity, note the appearance (typically white powder), molecular formula (C7H7NO2), and molecular weight (137.14). Ensure these meet your specific process requirements.
• Packaging and Storage: 6-Methylnicotinic Acid is often supplied in 25kg fiber drums. Proper storage conditions (dark, cool, ventilated, and dry environment) are essential to maintain its quality and shelf life.
• Pricing and Quotation: Requesting quotes from multiple suppliers is standard practice. The 6-methylnicotinic acid price can vary based on purity, order volume, and current market conditions. Compare offers not just on price, but also on the overall value provided by the manufacturer.

Navigating the Market: Manufacturers and Suppliers

The market for chemical intermediates can seem complex, with numerous manufacturers and distributors. When seeking a supplier, look for companies that specialize in organic intermediates and have a strong presence in both domestic and international markets. Companies offering comprehensive technical support and a clear understanding of regulatory requirements are highly advantageous. For instance, established manufacturers in China are well-positioned to serve global demand due to their advanced production capabilities and competitive pricing. Partnering with a manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to high-quality 6-Methylnicotinic Acid directly from a source committed to excellence.

Conclusion

Procuring 6-Methylnicotinic Acid effectively involves a strategic approach, focusing on purity, supplier credibility, and market awareness. By prioritizing these aspects, procurement managers can secure a vital intermediate that underpins critical pharmaceutical and chemical synthesis operations. Engaging with reputable manufacturers is key to ensuring a stable supply and maintaining the integrity of your research and production processes.