For professionals in the chemical and pharmaceutical industries, the consistent availability of high-quality raw materials is fundamental to successful research and development. Tert-boc-aminooxyacetic acid, also recognized by its CAS number 42989-85-5 and often abbreviated as Boc-AOA, is a vital chemical intermediate widely sought after for its unique properties in synthesis. This article aims to guide procurement managers and research scientists in understanding the importance of sourcing high-purity Boc-aminooxyacetic acid and identifying reliable suppliers and manufacturers.

Boc-aminooxyacetic acid is a bifunctional linking reagent characterized by its Boc (tert-butyloxycarbonyl) protecting group. This feature grants it enhanced stability and controlled reactivity, making it an excellent choice for chemists working on complex organic syntheses. Its primary applications lie in areas such as peptide synthesis, where it aids in creating modified amino acid sequences, and in drug development, where it serves as a key building block for novel therapeutic molecules. The ability to form stable oxime linkages via its aminooxy group is particularly valuable in bioconjugation strategies, enabling the precise attachment of molecules for targeted drug delivery or diagnostic purposes.

When considering the purchase of Boc-AOA, purity is a critical factor. A minimum purity of u226598% (HPLC) is often specified by researchers to ensure the integrity of their synthetic outcomes and to avoid the introduction of unwanted by-products. Identifying a manufacturer that rigorously controls its production processes and provides detailed quality certifications, such as Certificates of Analysis (COA), is therefore essential. Many global pharmaceutical and biotechnology companies rely on specialized chemical manufacturers in China for their supply of high-purity intermediates like Boc-aminooxyacetic acid, benefiting from both quality and competitive pricing.

For procurement managers tasked with sourcing this critical reagent, it is advisable to look for suppliers who offer a comprehensive range of services, including responsive customer support, flexible packaging options, and efficient logistics. Understanding the typical price points for Boc-AOA based on quantity and purity is also a key aspect of effective procurement. Engaging with manufacturers directly or through established distributors can provide insights into bulk purchase discounts and long-term supply agreements, ensuring continuity for ongoing research or production.

In summary, Boc-aminooxyacetic acid (CAS 42989-85-5) is a high-value chemical intermediate with significant applications in peptide synthesis and drug development. Prioritizing high purity and selecting a reputable manufacturer or supplier are crucial steps for any R&D team. By focusing on quality sourcing and understanding market dynamics, businesses can secure a reliable supply of Boc-AOA, paving the way for groundbreaking scientific advancements and the creation of next-generation therapeutics.