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Sourcing L-Lysine Ethyl Ester Dihydrochloride: A Buyer's Guide

For professionals in the pharmaceutical and biotechnology sectors, securing high-quality raw materials is paramount. L-Lysine ethyl ester dihydrochloride, commonly abbreviated as H-Lys-OEt·2HCl, is one such critical amino acid derivative widely used in peptide synthesis and as a building block for pharmaceutical intermediates. Understanding how to procure this compound effectively can significantly impact your R&D and production timelines.

H-Lys-OEt·2HCl, with the CAS number 3844-53-9, is chemically known as ethyl (2S)-2,6-diaminohexanoate dihydrochloride. It presents as a white powder, typically with a purity exceeding 98%, making it suitable for demanding applications. Its molecular formula is C8H18N2O2·2HCl, and its molecular weight is approximately 247.16 g/mol. These specifications are crucial for researchers and formulators to ensure compatibility and efficacy in their specific applications.

The primary utility of H-Lys-OEt·2HCl lies in its role as a protected lysine residue in the synthesis of peptides. During peptide synthesis, protected amino acids are sequentially coupled to a growing peptide chain. The ethyl ester protection of the carboxyl group and the dihydrochloride salt form of the amine groups provide the necessary stability and reactivity for efficient coupling reactions. This makes it an indispensable raw material for companies engaged in custom peptide synthesis, peptide-based drug discovery, and the development of novel biomaterials.

When looking to buy H-Lys-OEt·2HCl, it is essential to consider the reliability and quality offered by the manufacturer. Reputable suppliers, particularly those based in China, have established robust production processes and quality control measures to ensure consistent product specifications. These suppliers often provide detailed Certificates of Analysis (CoA) and Safety Data Sheets (SDS) to support your purchasing decisions. For procurement managers, identifying a dependable H-Lys-OEt·2HCl manufacturer or supplier is key to maintaining an uninterrupted supply chain for your critical projects.

The price of H-Lys-OEt·2HCl can vary based on quantity, purity, and supplier. Bulk purchases from direct manufacturers typically offer more competitive pricing, which is a significant consideration for large-scale operations. It is advisable to request quotes from several reputable suppliers to compare pricing and delivery terms. Engaging with manufacturers early in your project lifecycle can also help secure favorable terms and ensure long-term availability.

Furthermore, beyond its direct use in peptide synthesis, H-Lys-OEt·2HCl can also serve as a valuable intermediate in the broader field of organic synthesis and pharmaceutical development. Its diamine structure and ester functionality offer multiple reaction sites for chemists creating complex molecular architectures. Whether you are developing new APIs, agrochemicals, or specialty chemicals, understanding the sourcing landscape for essential building blocks like H-Lys-OEt·2HCl is a strategic advantage. Partnering with a trusted amino acid derivative supplier means investing in the quality and success of your end products.

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