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Sourcing N-alpha-Boc-L-lysine (CAS 13734-28-6): A Guide for Global Researchers

The global scientific community relies on a consistent and dependable supply of high-quality chemical reagents to drive innovation. N-alpha-(tert-Butoxycarbonyl)-L-lysine, known universally by its CAS number 13734-28-6 and the shorthand Boc-Lys-OH, is one such critical compound. For researchers involved in peptide synthesis, organic chemistry, and pharmaceutical development, understanding how to effectively source this essential amino acid derivative is crucial.

Boc-Lys-OH is a protected form of lysine, a naturally occurring amino acid. The tert-butoxycarbonyl (Boc) group attached to the alpha-amino nitrogen plays a pivotal role by preventing unwanted reactions during multi-step synthesis. This protection strategy is fundamental in peptide synthesis, allowing for the sequential addition of amino acids to build specific peptide sequences. Lysine also features an epsilon-amino group on its side chain, which might require separate protection depending on the synthetic route, adding to the versatility of Boc-Lys-OH as a building block.

When researchers decide to buy Boc-L-lysine online, several factors come into play, especially when considering international sourcing. The typical presentation of this chemical is as a white powder, with a molecular formula of C11H22N2O4 and a molecular weight of 246.30 g/mol. However, the most critical specification is purity, which should ideally be 95% or higher to ensure optimal reaction outcomes and reproducible results. Information regarding solubility, melting point, and optical activity can also be valuable for experimental planning.

The primary driver for the global demand for N-alpha-(tert-Butoxycarbonyl)-L-lysine is its indispensable role in both solid-phase and solution-phase peptide synthesis. It is also utilized in the creation of complex organic molecules, where its chiral nature and reactive functional groups can be exploited. As a pharmaceutical intermediate, it contributes to the synthesis of various drug candidates and active pharmaceutical ingredients (APIs).

For researchers seeking to source this compound, especially from international markets such as China, it is essential to partner with reputable manufacturers and suppliers. Key considerations include the supplier's track record, adherence to quality control standards, and the provision of comprehensive documentation, such as Certificates of Analysis (COAs). These documents confirm the identity, purity, and specifications of the product, providing confidence in its suitability for demanding research applications. Competitive pricing and reliable shipping logistics are also important factors in the procurement process.

In conclusion, N-alpha-(tert-Butoxycarbonyl)-L-lysine is a foundational component in modern chemical synthesis. By carefully selecting a trusted international supplier that offers high-purity Boc-Lys-OH, researchers can ensure the efficiency and success of their critical projects, driving forward advancements in science and medicine.

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