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For professionals in the pharmaceutical industry, securing a consistent and high-quality supply of key intermediates is paramount. One such crucial compound is 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one, identified by its CAS number 130049-82-0. This compound is a vital building block in the synthesis of Paliperidone, an important atypical antipsychotic medication used to treat schizophrenia and schizoaffective disorder.
Understanding the sourcing process for this pharmaceutical intermediate involves several key considerations. Firstly, the purity of the compound is critical. For pharmaceutical applications, a purity of 99% or higher is typically required to ensure the efficacy and safety of the final Active Pharmaceutical Ingredient (API). The appearance, often described as a pale-yellow solid, is another indicator of quality. The molecular formula C11H15ClN2O2 and molecular weight of 242.70 g/mol are essential for formulation and synthesis planning.
When looking to buy CAS 130049-82-0, it’s beneficial to partner with reputable manufacturers and suppliers. Companies specializing in fine chemicals and pharmaceutical intermediates, particularly those based in China, offer competitive pricing and a robust supply chain. Engaging with a manufacturer that provides detailed specifications, Certificates of Analysis (CoA), and comprehensive technical support can significantly streamline your procurement process.
For procurement managers and R&D scientists, identifying a reliable supplier for this specific intermediate is key to maintaining production timelines and research integrity. Many leading chemical suppliers offer this product, but it’s essential to verify their manufacturing capabilities, quality control processes, and ability to provide consistent batches. Enquiring about pricing and availability from multiple sources can help secure the best terms.
In summary, sourcing 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 130049-82-0) requires a focus on purity, supplier reliability, and understanding its role as a critical intermediate. By partnering with established manufacturers and requesting quotes, pharmaceutical companies can ensure they obtain this essential component for their vital drug synthesis needs.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
