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Sourcing Pharmaceutical Intermediates: The Role of CAS 146447-26-9

In the complex world of pharmaceutical manufacturing, the quality and reliability of chemical intermediates are paramount. One such critical compound is N-{4-[4-(Piperidinomethyl)pyridyl-2-oxy]-cis-2-butene}phthalimide maleic acid, identified by its CAS number 146447-26-9. This molecule plays a pivotal role as a key intermediate in the synthesis of Lafutidine, a widely used medication for gastrointestinal disorders.

For procurement managers and R&D scientists in the pharmaceutical sector, understanding the properties and sourcing implications of such intermediates is essential. N-{4-[4-(Piperidinomethyl)pyridyl-2-oxy]-cis-2-butene}phthalimide maleic acid, with its molecular formula C27H29N3O7, is typically supplied as a white crystalline powder. Its specified purity, often exceeding 99.0%, ensures that downstream reactions proceed efficiently and that the final Active Pharmaceutical Ingredient (API) meets stringent regulatory standards. The physical characteristics, such as its melting point around 150-151°C and its solubility in solvents like DMSO and methanol, are important considerations for process chemists when designing synthetic routes.

The significance of this intermediate is closely tied to the therapeutic applications of Lafutidine. Lafutidine is known for its efficacy in treating conditions such as gastric ulcers and erosive esophagitis. Therefore, a consistent and high-quality supply of its precursor, N-{4-[4-(Piperidinomethyl)pyridyl-2-oxy]-cis-2-butene}phthalimide maleic acid, is vital for pharmaceutical companies to maintain production and meet market demand. When looking to buy this essential chemical, it is crucial to partner with a reputable manufacturer and supplier, ideally one with a strong presence and robust quality control systems, such as those found in China.

Procurement of such specialized chemicals often involves detailed inquiries regarding pricing, packaging options (commonly 25kg drums), and logistical capabilities. A reliable supplier in China can offer competitive pricing, especially for bulk purchases, and ensure timely delivery to global destinations. Furthermore, working with an established chemical company means access to comprehensive technical support, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS), which are indispensable for regulatory compliance and safe handling within a laboratory or manufacturing environment.

In summary, for any pharmaceutical firm engaged in the synthesis of Lafutidine or similar compounds, securing a dependable source for N-{4-[4-(Piperidinomethyl)pyridyl-2-oxy]-cis-2-butene}phthalimide maleic acid (CAS 146447-26-9) is a strategic imperative. Prioritizing suppliers who demonstrate a commitment to quality, purity, and supply chain stability will ultimately contribute to the successful development and production of life-improving medications. If you are looking for this critical intermediate, consider partnering with experienced chemical manufacturers who can deliver consistent quality and value.

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