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Sourcing Prasugrel Intermediates: The Importance of p-toluenesulfonate Salts

The production of modern pharmaceuticals relies on a sophisticated supply chain, where the availability of critical intermediates dictates the pace and success of drug manufacturing. For antiplatelet medications like Prasugrel, specific intermediates are indispensable. Among these, 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one p-toluenesulfonate plays a pivotal role. Companies looking to buy or purchase these vital components must understand the advantages offered by this particular salt form.

This chemical compound, identified by its CAS number 952340-39-5, is recognized for its essential function as a precursor in the synthesis of Prasugrel. The inclusion of the p-toluenesulfonate group is not arbitrary; it confers significant advantages, most notably improved solubility in polar solvents compared to its free base form or other salts. This enhanced solubility is a key factor for efficient reaction kinetics and ease of processing in multi-step synthetic routes common in pharmaceutical manufacturing. For suppliers in China, offering this specific salt form caters to these critical process needs.

The efficacy of Prasugrel, a medication vital for preventing thrombotic events, is directly linked to the quality of its precursors. The purity of 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one p-toluenesulfonate, typically required to be 98% or higher, is paramount. This stringent requirement ensures that the final drug product is safe and effective, meeting global regulatory standards. NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a leading manufacturer, providing this high-quality intermediate to support the consistent production of Prasugrel, thereby contributing to patient health.

Furthermore, this intermediate acts as a versatile chemical building block with inherent nucleophilic properties, making it valuable for various synthetic transformations beyond the direct synthesis of Prasugrel. Researchers in pharmaceutical R&D can leverage its reactivity to explore new drug candidates or optimize existing synthetic pathways. Its reliable availability and well-defined properties as a chemical intermediate are cornerstones for innovation in medicinal chemistry, empowering scientists to develop next-generation therapeutics.

For pharmaceutical companies, securing a stable and reliable supply of high-quality intermediates is a strategic necessity. NINGBO INNO PHARMCHEM CO.,LTD. prides itself on being a proficient manufacturer in China, dedicated to meeting the stringent demands for compounds like 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridin-2(4H)-one p-toluenesulfonate. We understand the critical importance of each step in the pharmaceutical supply chain and are committed to supporting our clients’ success by providing intermediates that guarantee performance and quality.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
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