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Understanding the Specifications of 4-Hydroxy-alpha-aminoacetophenone Hydrochloride

For professionals in the chemical and pharmaceutical industries, understanding the precise specifications of raw materials is fundamental to successful research, development, and manufacturing. 4-Hydroxy-alpha-aminoacetophenone Hydrochloride (CAS 19745-72-3) is a chemical intermediate whose quality is defined by a set of critical parameters. Purchasers and R&D scientists must be familiar with these specifications to ensure they procure material that meets their project requirements.

The most common and crucial specification for this compound is its assay, typically stated as a minimum percentage purity. For 4-Hydroxy-alpha-aminoacetophenone Hydrochloride, a high purity level of ≥98% is standard from reputable manufacturers. This high assay indicates minimal impurities, which is vital for applications where even trace contaminants can affect reaction outcomes or the efficacy of the final product.

Another key identifier is the appearance. This intermediate is generally described as a white or off-white powder. Any deviation from this description, such as a significant discoloration or a different physical form, might suggest an issue with the material's quality or storage conditions.

Loss on drying is another important parameter, typically specified as a maximum percentage (e.g., ≤2.0%). This measures the amount of volatile matter, primarily moisture, present in the sample. Lower loss on drying indicates a more stable and concentrated product, which is desirable for accurate dosing and chemical reactions.

Heavy metals content is also critical, especially for pharmaceutical intermediates. Limits are usually set at a low parts per million (ppm) level, such as ≤10 ppm. This ensures that the compound is free from toxic metallic contaminants that could compromise drug safety.

When looking to buy 4-Hydroxy-alpha-aminoacetophenone Hydrochloride, especially from a China manufacturer, it is essential to cross-reference these specifications with your project needs. Leading suppliers will offer products that comply with international standards such as USP (United States Pharmacopeia), BP (British Pharmacopoeia), EP (European Pharmacopoeia), and FCC (Food Chemicals Codex), further reinforcing the quality and suitability for various applications. Understanding these specifications empowers buyers to make informed decisions when comparing prices from different suppliers and to ensure they are obtaining a high-quality chemical intermediate.

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