Sulfanilamide, identified by CAS number 63-74-1, stands as a foundational compound within the pharmaceutical industry. This substance is a white crystalline powder widely recognized as a vital pharmaceutical raw material. Its significance primarily lies in its potent antibacterial and antimicrobial properties, making it indispensable for various medical applications.

Structurally, Sulfanilamide bears a strong resemblance to p-aminobenzoic acid (PABA). Its mechanism of action is rooted in this similarity. Sulfanilamide effectively competes with PABA for the active site of the bacterial enzyme dihydropteroate synthase. This competitive inhibition prevents the crucial incorporation of PABA into dihydrofolic acid, which is the immediate precursor required for folic acid synthesis in bacteria. Consequently, the vital bacterial process of folic acid synthesis, along with the subsequent de novo synthesis of purines and pyrimidines essential for DNA and RNA, is inhibited. Without the ability to synthesize these critical components, bacterial growth is arrested, ultimately leading to cell death. This pathway highlights why Sulfanilamide, and the sulfa drugs derived from it, were pioneering antibacterial agents.

Beyond its direct antibacterial effect when applied topically, Sulfanilamide serves several key roles. It is the main raw material used in the synthesis of a wide range of sulfa drugs, a class of antibiotics historically and currently important in treating bacterial infections. Furthermore, Sulfanilamide functions as an intermediate in the synthesis of other pharmaceutical compounds and even certain agricultural chemicals like the herbicide asulam. It can also be utilized as a chemical reagent to determine the presence and concentration of nitrite.

The versatility of Sulfanilamide extends to veterinary medicine, where it is employed as a topical anti-inflammatory drug. Its broad-spectrum antibacterial activity is effective against various Gram-positive and negative bacteria, including but not limited to hemolytic streptococcus, Neisseria meningitidis, and Staphylococcus aureus. Historically and in some contexts, it has been used for wound disinfection and managing trauma infections caused by these bacteria. Its ability to be partially absorbed from a wound site contributes to its therapeutic effect in such applications. Notably, it has also been mentioned for its use in quickly stopping bleeding from wounds, although its primary role remains its antibacterial action.

Producing high-quality Sulfanilamide requires adherence to stringent standards such as USP, EP, BP, and CP. As a leading manufacturer and supplier of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. provides Sulfanilamide (CAS 63-74-1) meeting these rigorous specifications. For those looking to buy or purchase this essential powder, obtaining detailed specifications and competitive price information is readily available. Understanding the product's characteristics, standards, and packaging (typically in 25kg drums) is crucial for procurement. Information regarding minimum order quantity (MOQ) and available transport options ensures a smooth transaction process for prospective buyers seeking this reliable pharmaceutical raw material supplier.