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Exploring the Synthesis and Applications of 2-Aminobenzotrifluoride (CAS 88-17-5)

2-Aminobenzotrifluoride (CAS 88-17-5) is a cornerstone intermediate in modern organic synthesis, facilitating the creation of complex molecules vital to several key industries. Its unique chemical structure, featuring an amino group and a trifluoromethyl substituent on a benzene ring, makes it an indispensable tool for chemists seeking to introduce the powerful trifluoromethyl moiety. At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in the production and supply of high-purity intermediates like 2-Aminobenzotrifluoride, empowering innovation for our clients.

Chemical Properties and Synthesis Insights

As a colorless to light yellow liquid with a purity typically exceeding 99%, 2-Aminobenzotrifluoride (molecular formula C7H6F3N, molecular weight 161.12) exhibits reactivity characteristic of aromatic amines. The electron-withdrawing trifluoromethyl group significantly influences the electronic distribution of the benzene ring, affecting its reactivity in electrophilic and nucleophilic substitution reactions. While detailed synthesis pathways are proprietary, its production involves fluorination technologies and amination processes commonly employed in fine chemical manufacturing.

Its physical properties, such as a boiling point around 170-173°C and a refractive index of approximately 1.4800, are critical for process control and quality assessment. Understanding these properties is essential for any formulator or researcher looking to buy this compound.

Key Industrial Applications

The utility of 2-Aminobenzotrifluoride is broadly recognized across multiple sectors:

  • Agrochemicals: It serves as a crucial precursor for herbicides such as trifluralin, ethamflurane, and fluroxypyr. These compounds are vital for effective weed management in agriculture, contributing to food security and farm productivity. The ability to reliably purchase this intermediate impacts the efficiency and cost-effectiveness of herbicide production.
  • Pharmaceuticals: The trifluoromethyl group is a well-established pharmacophore, frequently incorporated into drug candidates to enhance lipophilicity, metabolic stability, and receptor binding. 2-Aminobenzotrifluoride is a direct pathway to introducing this advantageous group, making it highly valuable in drug discovery and development.
  • Dyes: In the dye industry, this intermediate can be used to synthesize specialized colorants, potentially offering improved lightfastness and color vibrancy due to the electronic influence of the trifluoromethyl group.

Sourcing Excellence from a Trusted Manufacturer

For professionals in these industries, securing a dependable source for 2-Aminobenzotrifluoride (CAS 88-17-5) is critical. As a leading supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers:

  • High-Quality Products: We guarantee a minimum purity of 99%, ensuring that your synthetic processes are efficient and your final products meet stringent quality standards.
  • Competitive Pricing: Our manufacturing capabilities allow us to offer attractive pricing for bulk orders, supporting your cost management objectives.
  • Reliable Supply: We maintain robust production and logistics to ensure timely deliveries, minimizing disruptions to your operations.

We encourage all potential customers to inquire about our 2-Aminobenzotrifluoride. Our team is ready to provide detailed specifications, quotations, and technical support to help you make an informed purchasing decision. Partner with us to secure a consistent and high-quality supply of this essential chemical intermediate.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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