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Exploring the Synthesis and Utility of 4'-(4-Methoxyphenyl)-2,2':6',2''-terpyridine

The advancement of chemical sciences often hinges on the availability and understanding of key intermediates that facilitate complex synthesis. This article explores 4'-(4-methoxyphenyl)-2,2':6',2''-terpyridine (CAS 13104-56-8), a significant organic synthesis intermediate, detailing its synthesis, properties, and diverse applications. For professionals looking to buy this compound, understanding its context is essential.

Synthesis and Properties

4'-(4-Methoxyphenyl)-2,2':6',2''-terpyridine (CAS 13104-56-8) is synthesized using established organic chemistry methods, often involving reactions that build the terpyridine core with the desired substituent. Typical synthesis routes might involve the condensation of appropriate pyridine precursors with an aldehyde bearing the methoxyphenyl group, followed by cyclization and purification steps. The resulting compound typically presents as a white crystalline powder, with a stated purity of 97% minimum. Its molecular formula is C22H17N3O, and it has a molecular weight of 339.39. The melting point is recorded around 167-168℃, and it is generally insoluble in water.

Industrial and Research Applications

The primary role of 4'-(4-methoxyphenyl)-2,2':6',2''-terpyridine is as an organic synthesis intermediate. Its structure lends itself to several important applications:

  • Pharmaceutical Industry: Used as a precursor for active pharmaceutical ingredients (APIs) or advanced intermediates in drug discovery and development.
  • Materials Science: Serves as a ligand for metal complex formation, leading to materials with tunable optical, electronic, or catalytic properties. These are useful in areas like luminescent displays, sensors, and catalysis.
  • Academic Research: A valuable compound for exploring new chemical reactions, coordination chemistry, and developing novel functional molecules.

Sourcing and Purchasing Strategies

When procurement managers need to secure supplies of 4'-(4-methoxyphenyl)-2,2':6',2''-terpyridine, they often look for reliable manufacturers and suppliers. Key factors in this decision include product purity, availability, lead times, and, importantly, price. Companies based in China are frequently cited as primary sources for such fine chemical intermediates due to their manufacturing capacity and competitive cost structures.

To ensure successful procurement, buyers should engage with suppliers who provide detailed product specifications, certificates of analysis, and safety data sheets. Requesting quotes for different quantities and comparing offers is a standard practice. Establishing a relationship with a consistent supplier can streamline future purchases and ensure uninterrupted project workflows.

In summary, 4'-(4-methoxyphenyl)-2,2':6',2''-terpyridine is an indispensable intermediate in modern chemistry. Its utility in pharmaceuticals and materials science, coupled with its availability from specialized manufacturers, makes it a cornerstone for innovation. For those looking to purchase this compound, careful supplier selection is key.

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