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Tankyrase Inhibition: Exploring XAV939's Mechanism and Sourcing Options

Tankyrase enzymes (TNKS1 and TNKS2) are key regulators within the Wnt signaling pathway, playing critical roles in cellular processes such as proliferation, differentiation, and stemness. Inhibiting these enzymes offers a promising therapeutic strategy, particularly in oncology and regenerative medicine. XAV939, with its CAS number 284028-89-3, is a well-characterized and potent inhibitor of Tankyrases, making it a compound of significant interest for researchers. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer in China, provides high-quality XAV939 to meet the global demand for this essential research chemical.

The mechanism of XAV939 involves binding to the NAD+ binding site of Tankyrase enzymes, thereby inhibiting their PARP activity. This inhibition leads to the stabilization of Axin proteins, which are part of the β-catenin destruction complex. Consequently, XAV939 effectively suppresses the canonical Wnt signaling pathway. Researchers looking to buy XAV939 for their studies can be assured of its efficacy in modulating Wnt signaling. NINGBO INNO PHARMCHEM ensures that our XAV939 product maintains a minimum purity of 98%, which is crucial for obtaining reliable and reproducible experimental data in biochemical assays and cellular studies.

As a primary manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. focuses on providing competitive XAV939 price points without compromising on quality. We understand the logistical challenges faced by researchers worldwide and have established a robust supply chain to ensure prompt and safe delivery of our products. If you are seeking to order XAV939, our experienced team is ready to assist you with obtaining a quotation and processing your purchase efficiently. We are committed to being your trusted source for critical research intermediates.

The scientific community's interest in Tankyrase inhibition and its therapeutic potential continues to grow. By supplying high-purity XAV939, NINGBO INNO PHARMCHEM aims to support these vital research efforts. We encourage scientists and procurement managers to contact us to discuss their specific requirements for XAV939 and to explore how our reliable supply and quality assurance can benefit their research projects. Partner with us for your chemical sourcing needs and contribute to the advancement of scientific knowledge.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
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