Taurocholic Acid, identified by CAS number 81-24-3, stands as a critical component within the complex biological system of bile acids. It is a conjugated bile acid, naturally synthesized in the liver through the process of conjugating cholic acid with taurine. This conjugation significantly alters the chemical properties of the bile acid, enhancing its solubility and emulsifying capabilities, which are paramount for its biological functions. As a secondary bile acid, it plays a fundamental role in the intricate processes of digestion and absorption of dietary fats, ensuring the efficient breakdown and uptake of lipids and fat-soluble vitamins in the small intestine.

The primary function of Taurocholic Acid in the digestive system revolves around its ability to act as a biological detergent. Upon secretion into the duodenum, it emulsifies large fat globules into smaller droplets, greatly increasing the surface area available for pancreatic lipases to act upon. This emulsification process is indispensable for the subsequent hydrolysis of triglycerides into free fatty acids and glycerol, which can then be absorbed across the intestinal wall. Without the action of bile acids like Taurocholic Acid, fat digestion and absorption would be severely impaired, leading to nutritional deficiencies and digestive discomforts.

Beyond its direct role in fat digestion, Taurocholic Acid participates in the enterohepatic circulation, a highly efficient recycling system where bile acids are reabsorbed in the ileum and returned to the liver via the portal vein. This extensive recycling minimizes the need for constant de novo synthesis by the liver, maintaining a sufficient pool of bile acids crucial for continuous digestive activity. This circulatory pathway also allows bile acids to act as signaling molecules, interacting with various receptors, including the farnesoid X receptor (FXR) and TGR5, influencing lipid, glucose, and energy metabolism, as well as maintaining the integrity of the intestinal barrier function.

The importance of Taurocholic Acid extends into its potential therapeutic and research applications. Its involvement in fat metabolism suggests roles in managing conditions related to lipid absorption and dyslipidemia. Studies indicate that modulating bile acid pools could influence cholesterol homeostasis, potentially contributing to the reduction of blood lipid levels. Furthermore, given its central role in liver-gut axis signaling and bile flow, Taurocholic Acid is a subject of research in the context of various liver diseases, including cholestasis, where impaired bile flow is a key issue. Its presence and metabolism are also investigated in relation to the gut microbiome, which significantly impacts the composition and activity of the bile acid pool.

As a high-purity raw material, Taurocholic Acid (CAS 81-24-3) with a typical assay of 98% or higher, presents as a white powder. Its molecular formula is C26H45NO7S, with a molecular weight of 515.7. These chemical specifications, along with its physical properties such as appearance and solubility, are crucial for its use in various applications, particularly in the pharmaceutical industry and scientific research. It is frequently employed as a reference standard in analytical chemistry to quantify bile acids in biological samples or to assess the purity of other bile acid derivatives used in medicinal formulations. Its consistent quality and purity are paramount for ensuring reliable results in research settings and predictable outcomes in potential therapeutic uses.

The demand for high-quality Taurocholic Acid powder underscores the need for reliable sourcing. For pharmaceutical research, diagnostic reagent manufacturing, or other scientific applications requiring this specific bile acid, securing a consistent supply of material meeting stringent quality standards is essential. Manufacturers producing this raw material adhere to rigorous quality control measures, often involving techniques like High-Performance Liquid Chromatography (HPLC) to verify purity and composition. Proper storage in cool, dry conditions is also critical to maintaining its stability and efficacy over its shelf life.

For entities seeking to procure Taurocholic Acid (CAS 81-24-3), understanding the supply chain is important. A reputable manufacturer and supplier can provide detailed specifications, quality documentation, and technical support. Inquiring about the current market price for various quantities is a standard step in the procurement process. The process to buy or purchase typically involves requesting a quotation, agreeing on terms, and arranging for logistics. Ensuring the supplier has experience in handling and shipping sensitive pharmaceutical raw materials internationally is also a key consideration.

Obtaining high-purity Taurocholic Acid (CAS 81-24-3) powder requires engaging with established players in the chemical and pharmaceutical raw material sector. The availability of comprehensive product information, including certifications and testing methods, provides assurance regarding the quality of the material. Whether for fundamental biological research, the development of novel therapeutic strategies, or analytical applications, access to a dependable source is critical. Exploring options to buy or purchase this essential bile acid involves evaluating potential suppliers based on their reputation, product quality, and logistical capabilities to ensure a seamless and reliable supply chain.

Investing in high-grade Taurocholic Acid raw powder from a trusted manufacturer and supplier is a strategic decision for any organization involved in relevant research or development. The critical role this molecule plays in biological processes and its potential in various applications make it a valuable commodity. Prospective buyers should carefully consider the source to guarantee the material meets their specific purity and regulatory requirements. Details regarding price and minimum order quantities can typically be obtained directly from the supplier, facilitating the decision-making and procurement process for those looking to purchase or buy Taurocholic Acid powder.