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For chemists and material scientists, a deep understanding of chemical intermediates' technical specifications is fundamental to successful synthesis and application. endo-3-Boc-aminotropane (CAS 132234-69-6) is one such compound, critical in various organic chemistry applications, particularly in the pharmaceutical sector. This article provides technical insights into its purity, key properties, and where to source it reliably.
Chemical Identity and Specifications
endo-3-Boc-aminotropane, identified by CAS number 132234-69-6, has the molecular formula C13H24N2O2 and a molecular weight of 226.32 g/mol. Its chemical structure is characterized by a bicyclo[3.2.1]octane ring system, with a Boc-protected amine group attached in the endo configuration at the 3-position. Typically, this compound is supplied with a high purity level, often specified as 98% or greater, which is essential for demanding synthetic applications where side reactions must be minimized.
Key Physical and Chemical Properties
The appearance of endo-3-Boc-aminotropane is generally described as a white to light yellow crystalline powder. While specific data on its solubility in various solvents might vary, it is generally soluble in common organic solvents used in synthesis. Important parameters for its handling and use include its density (around 1.07 g/cm³) and boiling point (approximately 339.8°C at 760 mmHg). The refractive index is also noted around 1.51. These properties are critical for chemists when designing reaction conditions and purification protocols. The presence of the Boc group offers protection to the amine, allowing selective transformations on other parts of the molecule before deprotection.
Sourcing High-Purity endo-3-Boc-aminotropane from China
For researchers and procurement specialists, sourcing this intermediate from reliable manufacturers in China is a common and effective strategy. Chinese chemical suppliers often provide endo-3-Boc-aminotropane with documented purity levels that meet stringent industry requirements. When you look to buy, prioritize suppliers who can furnish a Certificate of Analysis (CoA) detailing the purity and other key specifications. Furthermore, established manufacturers can offer competitive pricing, especially for bulk quantities, making it economically viable for both research and commercial production.
Applications and Further Research
The primary application of endo-3-Boc-aminotropane is as a precursor in the synthesis of various pharmaceuticals, including those with activity in the central nervous system. Its well-defined structure and reactivity make it a building block for complex molecular architectures. For those in need of this compound, reaching out to reputable Chinese manufacturers for a quote and sample is the most effective way to ensure quality and availability.
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