For scientists and engineers involved in pharmaceutical research, development, and production, a thorough understanding of the technical specifications of chemical compounds is essential. This includes detailed knowledge of their physical and chemical properties, which dictate their suitability for specific applications. In this article, we delve into the specifications of (alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic acid, identified by CAS number 156130-41-5, a critical pharmaceutical intermediate sourced from reputable manufacturers.

Key Chemical Identity and Properties

The compound (alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic acid, with the CAS number 156130-41-5, is characterized by its specific molecular structure. Its molecular formula is C23H29NO3, and its molecular weight is approximately 367.48 g/mol. These fundamental identifiers are crucial for analytical verification and ensuring the correct compound is being used in synthesis. The precise arrangement of atoms, including the chiral centers indicated by the stereochemical descriptors (alphaS,3R,4R), is critical for its intended use as a pharmaceutical intermediate, where stereospecificity can significantly impact biological activity.

Physical Appearance and Purity Standards

From a practical handling and application standpoint, the physical appearance of the compound is vital. (alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic acid is typically supplied as a white powder. This appearance is indicative of its purity. Reputable manufacturers, such as those in China specializing in fine chemicals, will provide a guaranteed purity level, often stated as ≥99%. This high level of purity is a critical requirement for pharmaceutical intermediates, as even minor impurities can affect the efficacy, safety, or stability of the final API. When procuring this material, always verify the purity specifications through the manufacturer's Certificate of Analysis.

Applications and Handling Considerations

As a pharmaceutical intermediate, this compound is primarily used in organic synthesis for the creation of more complex molecules, often APIs. Its specific chiral structure makes it a valuable building block in stereoselective synthesis pathways. When handling such fine chemicals, standard laboratory safety precautions should always be observed. Storage conditions recommended by the manufacturer, typically in a cool, dry place, are important to maintain the compound's integrity and purity over time. Suppliers usually offer various packaging options to suit different quantity requirements, from small R&D quantities to bulk packaging for industrial use.

Understanding these technical specifications allows researchers and procurement specialists to make informed decisions when sourcing (alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic acid. For reliable supply and accurate product information, engaging directly with established manufacturers who detail these critical parameters is always recommended.