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Tegafur API: A Deep Dive into its Chemical Properties and Manufacturing

Tegafur, with the CAS number 17902-23-7, is a fascinating molecule from a chemical perspective, crucial for its role in advanced cancer treatments. Its chemical name is 1-(tetrahydro-2-furyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione, and its molecular formula is C8H9FN2O3, with a molecular weight of approximately 200.17 g/mol. This structure is key to its function as a prodrug, which is activated within the body to release the potent antineoplastic agent, 5-fluorouracil (5-FU).

The physical properties of Tegafur API, typically described as a white to off-white crystalline powder, are important for its handling and formulation in pharmaceutical manufacturing. Its solubility characteristics – soluble in methanol and chloroform, slightly soluble in water and ethanol, and almost insoluble in benzene and ether – dictate the solvents and processes used in drug development. Understanding these properties is vital for optimizing drug delivery systems and ensuring the stability and bioavailability of the final medicinal product.

NINGBO INNO PHARMCHEM CO.,LTD. specializes in the meticulous manufacturing of Tegafur API, adhering to stringent production protocols. Our process involves precise chemical synthesis to ensure the highest purity and consistency, meeting critical pharmacopoeial standards such as CP and JP. The manufacturing process is carefully controlled to manage aspects like particle size and crystalline form, which can influence the API's performance in final drug formulations. Our expertise ensures that the Tegafur API we supply is of pharmaceutical grade.

The manufacturing of APIs like Tegafur requires specialized knowledge and adherence to Good Manufacturing Practices (GMP). NINGBO INNO PHARMCHEM CO.,LTD. is committed to these standards, ensuring that every batch of Tegafur API is produced under controlled conditions. This dedication to manufacturing excellence not only guarantees the quality of our product but also supports the pharmaceutical companies that rely on us for their critical drug development needs, particularly in the challenging field of oncology.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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