Terlipressin Acetate, a vital synthetic vasopressin analog, stands as a cornerstone in modern critical care. With its distinct chemical profile, including Chemical Name: Terlipressin Acetate, CAS.NO: 914453-96-6, Synonyms: Terlipressin Acetate, Molecular Formula C56H82N16O19S2, and Molecular Weight 1347.476, it is recognized for its high purity. Appearing as a white to off-white powder with an assay of ≥98.0%, this compound ensures pharmaceutical-grade quality for diverse applications.

Functioning as a prodrug, Terlipressin Acetate is transformed in vivo into (Lys8)-vasopressin by the removal of its N-terminal triglycine. This mechanism endows it with a longer duration of action and a superior safety profile compared to its parent compound. Terlipressin exhibits potent vasoconstrictive properties, primarily engaging the V1 receptor responsible for vasoconstriction, while also demonstrating activity on the V2 receptor, which contributes to maintaining the body's water balance. This dual action is crucial for its therapeutic benefits, particularly in stabilizing hemodynamic parameters.

The versatile clinical utility of Terlipressin Acetate extends across several critical conditions. It is extensively used in the management of acute variceal hemorrhage, especially severe bleeding from dilated veins in the esophagus (esophageal varices), where its vasoconstrictive effects help reduce blood flow and control bleeding. Furthermore, Terlipressin Acetate plays a significant role in improving kidney function in adults suffering from hepatorenal syndrome (HRS), particularly those experiencing a rapid reduction in kidney function. It is also indicated for norepinephrine-resistant septic shock, highlighting its importance in stabilizing patients with severe circulatory compromise. Its efficacy in treating HRS-acute kidney injury (AKI) has positioned it as a preferred vasoconstrictor in such cases.

NINGBO INNO PHARMCHEM CO.,LTD. adheres to stringent quality controls for Terlipressin Acetate. Our standard packaging includes 25 kg/drum, with flexible options available to meet specific customer requirements. For optimal preservation of its stability and efficacy, Terlipressin Acetate should be stored in a cool, ventilated place, protected from light. This ensures the integrity of the product from our facilities to its final application. Our commitment to excellence in manufacturing and supply chain management guarantees consistent product quality.

As a dedicated manufacturer and supplier of high-quality Terlipressin Acetate, NINGBO INNO PHARMCHEM CO.,LTD. is well-positioned to serve global pharmaceutical and research markets. We understand the critical importance of reliable sourcing for essential active pharmaceutical ingredients. For competitive price inquiries, or to buy/purchase Terlipressin Acetate, prospective partners are encouraged to reach out. Our robust production capabilities and commitment to customer satisfaction make us an ideal choice for those seeking a trustworthy and efficient supply chain partner for this crucial compound.