Tert-butyl N-(4-bromobutyl)carbamate, identified by CAS No. 164365-88-2, stands as a critical chemical intermediate in various advanced synthetic processes. This compound, often abbreviated as Boc-NH-C4-Br or tert-Butyl 4-bromobutylcarbamate, is highly valued for its unique molecular structure, which includes both a bromine atom and a protected amine group. Its versatility makes it an indispensable building block in the synthesis of complex organic molecules, particularly within the pharmaceutical industry.

Chemically, Tert-butyl N-(4-bromobutyl)carbamate has the molecular formula C9H18BrNO2 and a molecular weight of 252.15. Key physical properties include a predicted boiling point of approximately 308.8°C at 760 mmHg and a density of 1.228 g/cm3. It typically appears as an off-white low-melting solid. While its solubility is noted to be slight in common organic solvents like chloroform, ethyl acetate, and methanol, these characteristics are crucial for its handling and application in diverse chemical reactions.

The broad utility of Tert-butyl N-(4-bromobutyl)carbamate is evident across multiple scientific and industrial domains. In pharmaceutical synthesis, it serves as a vital precursor for several significant compounds. For instance, it is instrumental in the creation of N-Boc-aminoalkoxyphenyl derivatives, which are pharmacophore elements being explored for their potential in the treatment of glaucoma. Furthermore, this intermediate is essential for synthesizing various aloperine derivatives, compounds that show promise as anti-HIV agents. Its role extends to the modification of 4,5,6,7-tetrabromobenzotriazole (TBB) derivatives, leading to improved CK2 inhibitors. Beyond its pharmaceutical applications, Tert-butyl N-(4-bromobutyl)carbamate also functions effectively as a cross-linking reagent in other chemical processes, underscoring its broad applicability.

Ensuring the highest purity and consistent quality of Tert-butyl N-(4-bromobutyl)carbamate is paramount for its successful application in sensitive processes, especially in the pharmaceutical sector. Reputable chemical manufacturers adhere to stringent quality control standards, including ISO 9001:2015 certifications, to guarantee product integrity and performance. As a leading supplier in the market, we understand the critical need for reliable sourcing and efficient delivery. Our commitment is to provide bulk quantities of this high-quality chemical, offering competitive price options to meet diverse industrial and research demands.

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