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tert-Butyl N-(4-bromobutyl)carbamate: A Key Building Block for Chemical Synthesis

The field of organic chemistry relies heavily on versatile building blocks that can be manipulated to construct complex molecular architectures. tert-Butyl N-(4-bromobutyl)carbamate, identified by CAS 164365-88-2, is a prime example of such a crucial intermediate. Its unique structure, featuring both a reactive bromide and a protected amine, makes it indispensable for researchers and manufacturers engaged in pharmaceutical development, agrochemicals, and fine chemical synthesis. This article aims to inform B2B buyers about the applications and sourcing best practices for this essential compound.

Chemical Profile and Reactivity of tert-Butyl N-(4-bromobutyl)carbamate

tert-Butyl N-(4-bromobutyl)carbamate (also known by synonyms such as N-Boc 4-bromobutan-1-amine) possesses a molecular formula of C9H18BrNO2 and a molecular weight of 252.15. The Boc (tert-butoxycarbonyl) protecting group on the amine renders it stable under various reaction conditions, while the primary alkyl bromide offers a site for nucleophilic substitution reactions. This bifunctionality allows for stepwise reactions, making it an excellent precursor for introducing a four-carbon chain with a protected amine functionality into larger molecules. When you buy this chemical, understanding its reactivity is key to designing efficient synthetic routes.

Applications in Pharmaceutical and Chemical Industries

The primary utility of tert-Butyl N-(4-bromobutyl)carbamate lies in its role as a pharmaceutical intermediate. It is employed in the synthesis of various drug candidates, including those targeting viral infections like HIV and certain types of protein kinases, such as CK2 inhibitors. Its ability to be incorporated into molecular frameworks makes it valuable for constructing complex pharmacophores. Beyond pharmaceuticals, it serves as a general building block in fine chemical synthesis, enabling the creation of novel organic compounds for research and development purposes. For scientists looking to buy, its versatility ensures a broad range of potential applications.

Sourcing tert-Butyl N-(4-bromobutyl)carbamate: Quality and Reliability

Procuring high-quality tert-Butyl N-(4-bromobutyl)carbamate is critical for reliable synthesis. B2B buyers should seek manufacturers and suppliers who can guarantee purity levels typically above 98%, along with comprehensive Certificates of Analysis (CoAs). When you need to purchase this intermediate, focusing on suppliers with established reputations in the chemical industry, especially those with significant operations in China, can offer advantages in terms of both price and consistent supply. Look for suppliers who are transparent about their manufacturing processes and quality control measures.

Finding the Best Supplier and Price

To source effectively, utilize online chemical platforms and directories to compare offers from various manufacturers. When requesting a quote for tert-Butyl N-(4-bromobutyl)carbamate, clearly state the CAS number (164365-88-2), the required quantity, and any specific purity or packaging requirements. Engaging directly with manufacturers, particularly for bulk orders, often leads to more competitive pricing. Consider the supplier's logistical capabilities, including shipping times and methods, to ensure your procurement aligns with your project timelines. Partnering with a reliable supplier for this essential building block will undoubtedly enhance your synthesis projects.

In essence, tert-Butyl N-(4-bromobutyl)carbamate is a fundamental intermediate whose strategic procurement empowers advancements across various chemical and pharmaceutical sectors.

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