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Tert-Butylchlorodiphenylsilane: A Key Reagent for Pharmaceutical Synthesis

The pharmaceutical industry relies heavily on precise chemical transformations to develop life-saving drugs and treatments. Within this complex landscape, specialized reagents like tert-Butylchlorodiphenylsilane (TBDPSCl), CAS 58479-61-1, play an indispensable role. As a potent silylating agent and a vital intermediate, TBDPSCl is instrumental in protecting sensitive functional groups during the synthesis of Active Pharmaceutical Ingredients (APIs). For procurement managers and R&D scientists, understanding the value and sourcing options for this compound is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier, dedicated to providing high-quality TBDPSCl to the global pharmaceutical market.

TBDPSCl's primary function as a silylating agent allows chemists to selectively protect hydroxyl, amino, and carboxyl groups. The tert-butyldiphenylsilyl (TBDPS) group offers superior steric bulk and electronic properties compared to simpler silyl protecting groups like tert-butyldimethylsilyl (TBS). This increased stability translates to greater resistance against a wider array of reaction conditions, including acidic hydrolysis, which is a significant advantage in complex synthetic routes. When embarking on projects that require a reliable silyl ether preparation reagent, TBDPSCl often emerges as the preferred choice due to its robustness and the ability to achieve selective deprotection under carefully controlled acidic conditions.

The importance of TBDPSCl in pharmaceutical development cannot be overstated. It acts as a cornerstone intermediate in the synthesis of various complex organic molecules, including nucleoside analogues and other therapeutic agents. By reliably protecting reactive sites, it enables chemists to carry out intricate modifications on other parts of a molecule without compromising the integrity of the protected groups. This efficiency directly impacts the feasibility and cost-effectiveness of drug manufacturing processes. For organizations looking to buy tert-Butylchlorodiphenylsilane, securing a consistent supply of high-purity material from a trusted tert-Butylchlorodiphenylsilane manufacturer is paramount to ensuring the quality and yield of their final pharmaceutical products.

When considering where to purchase TBDPSCl, factors such as purity, availability, and pricing are critical. As a prominent tert-Butylchlorodiphenylsilane supplier in China, we are committed to meeting these requirements. Our state-of-the-art manufacturing facilities ensure that the TBDPSCl we supply consistently adheres to high purity standards (≥98.5% GC), making it suitable for the most demanding pharmaceutical applications. We understand the critical nature of the supply chain in this sector, and we strive to offer competitive CAS 58479-61-1 price points without compromising on quality.

Furthermore, the synthesis of TBDPSCl is a specialized process that demands expertise in organosilicon chemistry. By partnering with us, pharmaceutical companies gain access to a reliable source of this essential building block, allowing their R&D and production teams to focus on innovation and drug discovery. We are dedicated to supporting the pharmaceutical sector by providing the high-quality chemical intermediates necessary for bringing groundbreaking therapies to market.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
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