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Tetramethylammonium Chloride: Enhancing DNA Stabilization and PCR Efficiency

In the realm of biotechnology and molecular biology, precision and efficiency are paramount. Tetramethylammonium Chloride (TMAC), a chemical compound with the CAS number 75-57-0, plays a significant role in enhancing the efficacy of techniques like Polymerase Chain Reaction (PCR). NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of high-purity reagents for these sensitive applications and highlights TMAC's contribution to DNA stabilization.

PCR is a cornerstone technique for amplifying specific DNA sequences. The efficiency and specificity of PCR can be significantly influenced by various factors, including the presence of certain salts and additives. TMAC, when used in low concentrations, has been shown to act as a DNA stabilizer. It achieves this by interacting with the DNA molecule, specifically stabilizing the adenine-thymine (AT) base pairs. This stabilization leads to a preferential melting of AT-rich regions compared to guanine-cytosine (GC) rich regions, thereby increasing the fidelity and yield of the amplified DNA.

NINGBO INNO PHARMCHEM CO.,LTD. provides TMAC that meets the stringent purity requirements for molecular biology applications. Researchers can buy Tetramethylammonium Chloride from NINGBO INNO PHARMCHEM CO.,LTD. to improve their PCR results, achieving yield enhancements of 5-10 fold at approximately 60mM concentration. This makes TMAC a valuable tool for genetic research, diagnostics, and other DNA-amplification-dependent scientific endeavors. The ability to acquire reliable Tetramethylammonium Chloride for DNA stabilization is crucial for reproducible experimental outcomes.

The chemical's ability to enhance specificity in PCR means that fewer non-target DNA sequences are amplified, leading to cleaner and more interpretable results. This is particularly important in complex genetic samples or when working with low amounts of starting DNA. As a leading Tetramethylammonium Chloride supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers with the tools they need to push the boundaries of scientific discovery. The insights into Tetramethylammonium Chloride applications in PCR demonstrate its critical role in modern biotechnology.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

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  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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