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Tetramethylsilane (TMS): The Essential Standard for NMR & Synthesis

NINGBO INNO PHARMCHEM CO.,LTD. is proud to present Tetramethylsilane (TMS), a high-purity organosilicon compound crucial across a variety of scientific and industrial applications. Known by its chemical formula Si(CH3)4 and CAS number 75-76-3, TMS is a colorless, transparent liquid with an assay of 98% or higher, signifying its exceptional quality and reliability.


At the forefront of its utility, Tetramethylsilane serves as the universal internal standard in Nuclear Magnetic Resonance (NMR) spectroscopy. Its unique molecular structure, featuring twelve equivalent hydrogen atoms, results in a single, sharp signal in 1H NMR spectra, which is conventionally assigned a chemical shift of zero (δ=0.0 ppm). This distinct and isolated resonance ensures accurate calibration and precise measurement of chemical shifts for other protons within a sample. Similarly, in 13C and 29Si NMR spectroscopy, the equivalence of its carbon and silicon atoms makes TMS an ideal reference, providing clear and unambiguous signals for calibration. Its high shielding effect on hydrogen atoms ensures that most sample signals appear downfield, preventing interference and simplifying spectral analysis. The chemical inertness of TMS further guarantees that it will not react with the sample, maintaining the integrity of the analysis. Furthermore, its inherent volatility allows for easy removal after the NMR experiment, making sample recovery straightforward and efficient.


Beyond its indispensable role in analytical chemistry, Tetramethylsilane is also a valuable intermediate in various synthetic processes. It is employed as a precursor in Chemical Vapor Deposition (CVD) techniques for the fabrication of advanced materials, including silicon dioxide and silicon carbide films. These applications are critical in the semiconductor industry and in the development of specialized coatings. Moreover, TMS acts as a foundational building block in organometallic chemistry, enabling the synthesis of more complex organosilane compounds. For instance, its reaction with butyl lithium yields tetramethylsilyl lithium, a versatile alkylating agent essential in organic synthesis. It also serves as an intermediate for the production of α-SiC:H thin films via Plasma Enhanced Chemical Vapor Deposition (PECVD), demonstrating its versatility in advanced material science.


The physical properties of Tetramethylsilane contribute to its broad applicability. It is a highly volatile liquid, characterized by a low boiling point of approximately 26.6 °C and a density of 0.648 g/cm³. While it exhibits low solubility in water (around 20 mg/L), it is highly soluble in most common organic solvents, making it compatible with a wide range of chemical environments. With a melting point of -99.06 °C and a flash point of -28 °C, proper handling and storage are imperative due to its extremely flammable nature. NINGBO INNO PHARMCHEM CO.,LTD. ensures that all products, including TMS, meet stringent safety and quality standards.


As a leading manufacturer and supplier of high-quality chemical compounds, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing Tetramethylsilane (TMS) that meets the rigorous demands of research, development, and industrial production. For detailed product specifications, current price information, or to discuss your specific requirements and purchase options, please reach out to our dedicated sales team. We offer competitive pricing and flexible delivery solutions to support your projects globally. Trust NINGBO INNO PHARMCHEM CO.,LTD. for your Tetramethylsilane needs, ensuring purity and performance in every application.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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