Tetraphenylphosphonium Bromide (TPPBr): A Keystone in Advanced Chemical Synthesis

Tetraphenylphosphonium Bromide, with the chemical name TETRAPHENYLPHOSPHORUS BROMIDE and CAS number 2751-90-8, stands as a highly valued compound in the realm of modern chemistry. This versatile quaternary phosphonium salt, often abbreviated as TPPBr, is critically important across numerous industrial and research applications, primarily recognized for its efficacy as a phase-transfer catalyst. As a dedicated manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is proud to offer high-purity TPPBr, meeting the stringent demands of global markets.

Unveiling the Properties of TPPBr

TPPBr presents as a white to off-white crystalline powder, indicative of its high purity and stable chemical structure. Its molecular formula, C24H20BrP, gives it a molecular weight of 419.293. This compound exhibits a melting point typically ranging from 295 to 300 °C, and a flash point of 260 °C, highlighting its thermal stability. Our Tetraphenylphosphonium Bromide consistently achieves an assay of 99%, ensuring reliability and optimal performance in diverse chemical processes. The rigidity of its phenyl groups contributes to its excellent packing properties, facilitating easy crystallization and enhancing its overall utility.

The Power of Phase-Transfer Catalysis

The principal application of Tetraphenylphosphonium Bromide lies in its exceptional capability as a phase-transfer catalyst. In chemical reactions, especially those involving immiscible phases, TPPBr acts as a bridge, effectively transferring ionic reactants from an aqueous phase to an solvent-based organic phase where the reaction can proceed more efficiently. This unique property significantly enhances reaction rates, yields, and selectivity, while simplifying synthetic procedures and reducing environmental impact by minimizing the use of harsh solvents. It is particularly indispensable in the synthesis of complex organic molecules, allowing for reactions that would otherwise be challenging or impractical.

Broadening Horizons: Diverse Applications of TPPBr

Beyond its crucial role in phase-transfer catalysis, Tetraphenylphosphonium Bromide finds extensive utility across a spectrum of cutting-edge applications:

• Organic Synthesis: It is widely employed in creating lipophilic salts from inorganic and organometallic anions, enabling the dissolution of inorganic anions in organic solvents, which is vital for many synthetic pathways.


• Biological Research: TPPBr serves as an invaluable tool in investigating cellular processes, including studies on mitochondrial function and membrane transport phenomena. Its ability to selectively permeate biological membranes opens avenues for innovative approaches in drug delivery and cellular imaging.


• Electrochemistry: Due to its unique electrochemical properties, TPPBr is utilized in the development of novel materials for advanced batteries and sensitive sensors.


• Material Science: It plays a significant role in the synthesis of phosphonium-based polymers, which are integral to various applications, including high-performance coatings and robust adhesives, owing to their enhanced stability and performance characteristics.


• Pharmaceutical Development: In the pharmaceutical industry, researchers leverage TPPBr in drug formulation processes to improve drug solubility and bioavailability, leading to more effective therapeutic agents.

NINGBO INNO PHARMCHEM CO.,LTD.: Your Trusted Partner

As a leading manufacturer and supplier of high-quality chemical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. specializes in a comprehensive range of quaternary ammonium salt products, exceeding 200 different types. Our portfolio covers high-content powder, crystal, and paste forms, as well as low-content liquid and paste variants, alongside specialized and quaternary ammonium alkali products. We are committed to providing exceptional product quality and customized services to meet specific customer requirements.

Our research and development efforts are continuously focused on innovation, particularly in areas like oilfield chemicals, pesticide emulsifiers, disinfectants for aquatic products, and surfactants designed for daily chemical applications with unique performance criteria. This dedication ensures that in addition to conventional surfactant products, we can also customize various specialized surfactant solutions to address the unique demands of diverse industries.

For detailed price information, to buy or to purchase Tetraphenylphosphonium Bromide, or to explore our extensive range of chemical products, please reach out to our sales team. We are dedicated to delivering reliable, high-purity chemicals and outstanding service to our global clientele. Our products are typically available in 25 kg drums, with flexible packaging options to accommodate specific customer needs, and should be stored in a cool, ventilated place to maintain their integrity.