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The Chemical Profile of 5-Bromo-2-dimethylaminopyridine for Synthesis Applications

For chemists engaged in the synthesis of complex organic molecules, understanding the fundamental properties and reaction potential of their starting materials is crucial. 5-Bromo-2-dimethylaminopyridine (CAS 26163-07-5) is a heterocyclic compound that has garnered significant attention as a versatile intermediate, especially within the pharmaceutical and fine chemical sectors. Its unique structural features make it an attractive building block for creating novel chemical entities.

At its core, 5-Bromo-2-dimethylaminopyridine is a pyridine derivative. The pyridine ring is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of the bromine atom at the 5-position and the dimethylamino group at the 2-position imparts distinct reactivity patterns. The bromine atom serves as an excellent leaving group or a point for cross-coupling reactions, such as Suzuki, Stille, or Buchwald-Hartwig couplings, which are fundamental in modern synthetic organic chemistry. The dimethylamino group, being an electron-donating substituent, can influence the electronic properties of the pyridine ring and may also participate in certain reactions or serve as a directing group.

The typical purity specification for this compound is 99%, a testament to the advanced manufacturing processes employed by leading chemical suppliers. This high level of purity is critical for chemists to achieve reproducible results and avoid unwanted side reactions or purification challenges. When looking to buy this compound, understanding its physical state (often a powder) and its molecular weight (201.0638 g/mol) is also important for stoichiometric calculations and handling.

Chemists often seek out intermediates like 5-Bromo-2-dimethylaminopyridine because it allows for the streamlined synthesis of more complex pyridine-containing structures. These structures are frequently found in biologically active molecules, including pharmaceuticals and agrochemicals. Therefore, manufacturers and suppliers who can consistently deliver this high-quality intermediate play a vital role in the R&D pipeline for many industries.

For organizations looking to purchase 5-Bromo-2-dimethylaminopyridine, partnering with a reliable manufacturer in China offers distinct advantages, including competitive pricing and consistent availability. Ensuring that the supplier can meet your specific purity requirements and deliver reliably is key to successful procurement. This compound represents a valuable tool for any synthetic chemist aiming to build molecular complexity efficiently.

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