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Understanding the precise chemical and physical properties of pharmaceutical intermediates is fundamental for their effective utilization in complex synthetic processes. Ethyl 2-(2-formamidothiazol-4-yl)acetate, with its CAS number 64987-05-9, is a prime example of an intermediate where detailed knowledge of its characteristics is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive data on this compound to facilitate its optimal application in the synthesis of antibiotics like Ceftazidime and Aztreonam.
The chemical name itself, Ethyl 2-(2-formamidothiazol-4-yl)acetate, reveals key structural elements: an ethyl ester, a formamide group, and a thiazole ring. This specific combination contributes to its reactivity and its suitability as a precursor for advanced pharmaceutical molecules. With a molecular formula of C8H10N2O3S and a molecular weight of 214.24200, its chemical profile is well-defined. The product, typically appearing as an off-white to pale yellow powder, is meticulously manufactured to achieve a high purity of ≥98.0%.
Beyond its molecular structure, a range of physical properties are critical for handling and processing. These include its density (1.354), melting point (130-132°C), boiling point (314.4°C), flash point (160.3°C), and refractive index (1.586). This data, provided by NINGBO INNO PHARMCHEM CO.,LTD., enables chemists and process engineers to accurately plan reaction conditions, safety protocols, and storage requirements. The precise melting point, for instance, is a key indicator of purity and batch consistency.
The primary application of Ethyl 2-(2-formamidothiazol-4-yl)acetate is in the synthesis of Ceftazidime and Aztreonam, two critically important antibiotics. The ability to consistently produce these life-saving drugs relies heavily on the quality and well-characterized nature of their intermediates. NINGBO INNO PHARMCHEM CO.,LTD. ensures that manufacturers have access to reliable data and a high-quality product, supporting the development and production of effective pharmaceuticals that address significant global health needs.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
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