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Indometacin, a staple in the pharmaceutical industry, owes its therapeutic efficacy to a precise chemical profile. At NINGBO INNO PHARMCHEM CO.,LTD., we understand that the detailed chemical properties of Indometacin are fundamental to its application as an anti-inflammatory and analgesic drug. This article provides an in-depth look at the chemical nature of Indometacin (CAS 53-86-1) and its significance in pharmaceutical manufacturing.
The chemical formula of Indometacin is C19H16ClNO4, with a molecular weight of approximately 357.79 g/mol. Its structure, a derivative of indole acetic acid, is key to its function as a non-steroidal anti-inflammatory drug (NSAID). Indometacin is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, thereby blocking the synthesis of prostaglandins. This inhibition is a direct result of its molecular structure and how it interacts with the active sites of these enzymes. Understanding the Indometacin mechanism of action as a COX inhibitor is crucial for formulators working with this compound.
The physical and chemical properties of Indometacin, such as its appearance as a white to off-white crystalline powder and its solubility characteristics, are critical considerations when one decides to buy Indometacin pharmaceutical powder. While it is sparingly soluble in water, it exhibits better solubility in organic solvents like DMF, ethanol, and chloroform. These solubility patterns influence the formulation strategies for Indometacin-based medications, affecting drug delivery and bioavailability. Ensuring the Indometacin raw material pharmaceutical grade possesses consistent solubility is a priority for NINGBO INNO PHARMCHEM CO.,LTD.
The Indometacin CAS 53-86-1 properties also include its melting point, typically in the range of 211-216 °C, and its stability under specific storage conditions. Proper storage is essential to maintain its potency and prevent degradation. Pharmaceutical manufacturers rely on suppliers like NINGBO INNO PHARMCHEM CO.,LTD. to provide Indometacin with documented stability data and adherence to storage recommendations. This commitment ensures that the pharmaceutical powder maintains its integrity from our facility to yours.
In conclusion, the chemical profile of Indometacin is integral to its widespread use as an effective anti-inflammatory analgesic drug. Its specific molecular structure and physicochemical properties dictate its therapeutic action and formulation possibilities. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing Indometacin that meets the highest standards of chemical purity and consistency, empowering pharmaceutical companies to develop safe and effective treatments. Trust us to be your source for quality pharmaceutical chemicals.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
