Understanding the fundamental chemical properties of a compound is paramount for its effective utilization in synthesis and research. Cyclobutanone (CAS 1191-95-3), a four-membered cyclic ketone, possesses a unique reactivity profile that makes it an indispensable tool in the chemist's arsenal. This article explores the key chemical characteristics of Cyclobutanone and its significant applications, drawing insights from leading manufacturers like NINGBO INNO PHARMCHEM CO.,LTD.

Chemical Structure and Properties of Cyclobutanone

Cyclobutanone, with the molecular formula C4H6O, features a strained four-membered ring containing a carbonyl group. This inherent ring strain influences its reactivity compared to larger cyclic ketones or acyclic ketones. Key physical and chemical properties include:

• Molecular Weight: Approximately 70.09 g/mol.
• Appearance: Typically a clear, colorless to slightly yellow liquid.
• Boiling Point: Around 99°C (lit.), indicating its volatility and suitability for distillative purification.
• Density: Approximately 0.938 g/mL at 25°C, less dense than water.
• Solubility: Generally insoluble in water but miscible with many organic solvents.
• Reactivity: The carbonyl group is susceptible to nucleophilic attack, similar to other ketones. However, the ring strain can also play a role in specific reactions, such as ring-opening reactions under certain conditions. It readily undergoes alpha-functionalization reactions.

Applications Driven by Reactivity

The chemical properties of Cyclobutanone dictate its wide range of applications:

• Pharmaceutical Intermediates: Cyclobutanone is a crucial building block for synthesizing numerous active pharmaceutical ingredients (APIs). Its structure can be incorporated into complex drug molecules to confer specific pharmacological properties. For example, it's used in the synthesis of certain anti-cancer agents and neurological drugs. When you buy high-purity Cyclobutanone, you are investing in the foundational elements of drug discovery.
• Organic Synthesis: In academic and industrial research laboratories, Cyclobutanone serves as a versatile starting material for various organic transformations. It can be used in Grignard reactions, Wittig reactions, aldol condensations, and as a precursor for other cyclobutane derivatives.
• Fine Chemicals: Beyond pharmaceuticals, Cyclobutanone finds application in the synthesis of other fine chemicals, including specialty polymers, agrochemicals, and advanced materials. Its unique structural motif can impart desired properties to the final products.
• Research and Development: Its straightforward synthesis and diverse reactivity make it a popular choice for developing new synthetic methodologies and exploring novel chemical entities.

Sourcing High-Quality Cyclobutanone

To harness the full potential of Cyclobutanone in your applications, sourcing from a reputable manufacturer is essential. NINGBO INNO PHARMCHEM CO.,LTD. provides high-purity Cyclobutanone (CAS 1191-95-3) that meets stringent quality standards. We understand the critical role this intermediate plays and are dedicated to ensuring its consistent availability and quality for our clients. Request a quote today to experience the reliability of our supply and the purity of our products.