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4-Isopropyl-1H-pyrazol-3-amine (CAS 151521-49-2) is a fine chemical that plays a pivotal role as an intermediate in various advanced synthesis processes, most notably within the pharmaceutical industry. Understanding its synthesis and properties is key for any chemist or procurement specialist looking to leverage this versatile molecule. As a manufacturer, we recognize the importance of providing not just the product, but also insight into its creation and utility.
Understanding the Molecule: Structure and Properties
This compound is characterized by a pyrazole ring system, which is a five-membered heterocycle containing two adjacent nitrogen atoms. Attached to this core structure are an isopropyl group and an amine group. The presence of the amine group (-NH2) makes it a primary amine, readily capable of undergoing reactions such as acylation, alkylation, and condensation. The isopropyl group (-CH(CH3)2) contributes to the molecule's steric profile and lipophilicity. Typically, it presents as a golden brown solid, with a density of approximately 1.104. Its molecular formula is C6H11N3, and its molecular weight is 125.17 g/mol.
The Synthesis Pathway
While specific proprietary synthesis routes may vary among manufacturers, the general approach to creating 4-Isopropyl-1H-pyrazol-3-amine often involves multistep organic reactions starting from readily available precursors. Common strategies might include:
The efficiency and scalability of these synthesis pathways are crucial for a manufacturer aiming to produce high-purity material at a competitive price. Rigorous process control and optimization are undertaken to ensure consistent yields and minimize unwanted by-products, which is essential for meeting the demanding purity requirements for pharmaceutical intermediates.
Applications Driving Demand
The primary demand for 4-Isopropyl-1H-pyrazol-3-amine stems from its role as a key intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its structural features make it adaptable for incorporation into a wide range of drug candidates targeting various therapeutic areas. Beyond pharmaceuticals, it also finds applications in:
The Manufacturer's Commitment to Quality
As a dedicated manufacturer, our focus is on delivering 4-Isopropyl-1H-pyrazol-3-amine that meets stringent quality standards. This includes ensuring high purity, lot-to-lot consistency, and providing comprehensive documentation such as Certificates of Analysis. When you choose to buy from us, you are partnering with a supplier committed to enabling your synthesis success through reliable and high-quality chemical intermediates.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
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