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The Chemistry of 4-Bromo-1-methylpiperidine: Properties and Synthesis Insights

Understanding the fundamental chemical properties and synthesis routes of key intermediates is essential for advancing organic chemistry and its applications. 4-Bromo-1-methylpiperidine, identified by CAS 76444-51-4, is a heterocyclic organic compound that holds significant value as a versatile building block. Its structure, featuring a saturated six-membered nitrogen-containing ring with a bromine atom at the 4-position and a methyl group at the nitrogen atom, dictates its reactivity and utility in various synthetic pathways.

The physicochemical properties of 4-bromo-1-methylpiperidine are critical for its effective use. With a molecular formula of C6H12BrN and a molecular weight of approximately 178.07 g/mol, it exhibits a boiling point of around 174.768°C at atmospheric pressure and a flash point of 59.498°C. These parameters are vital for safe handling, storage, and reaction design. As a supplier and manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. ensures that these properties are well-documented and understood by our clients. The compound is generally described as stable under normal conditions, making it a reliable component in complex synthetic schemes.

The synthesis of 4-bromo-1-methylpiperidine typically involves chemical transformations that introduce the bromine atom and the methyl group onto a piperidine core. While specific proprietary synthesis routes may vary, common approaches often involve alkylation of a brominated piperidine derivative or bromination of an N-methylated piperidine. The ability to produce this intermediate efficiently and at high purity is a hallmark of advanced chemical manufacturing. NINGBO INNO PHARMCHEM CO.,LTD. leverages its expertise in heterocyclic chemistry to provide access to such critical organic synthesis building blocks.

The reactivity of the C-Br bond in 4-bromo-1-methylpiperidine is a key feature that enables its use in a wide array of reactions. This includes nucleophilic substitutions, cross-coupling reactions, and other transformations that are fundamental to constructing more complex molecular architectures. These reactions are vital for creating new pharmaceuticals, agrochemicals, and functional materials. NINGBO INNO PHARMCHEM CO.,LTD. supports these endeavors by supplying high-quality heterocyclic organic compounds that serve as reliable starting points for innovation. The availability of such intermediates is crucial for research laboratories and industrial production alike.

In summary, a thorough understanding of the chemical properties and synthesis routes of 4-bromo-1-methylpiperidine is fundamental to its successful application in organic synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing comprehensive information and high-quality products to facilitate scientific and industrial progress in chemistry.

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