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Understanding the chemical properties of intermediates is fundamental to their effective utilization in synthesis. 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene (CAS: 105529-58-6) is a compound whose structure dictates its reactivity and broad applicability in fine chemical production. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier that ensures this compound’s specifications are precisely met.
Physically, 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene is described as a liquid, typically colorless to light yellow, with a boiling point of 78°C at 48 torr and a density of approximately 1.71 g/cm³. Its molecular formula, C7H3BrF4O, reveals a benzene ring substituted with a bromine atom at position 4, a fluorine atom at position 2, and a trifluoromethoxy group (-OCF3) at position 1. This unique arrangement of electronegative groups significantly influences the electronic distribution within the aromatic ring, activating or deactivating specific positions for electrophilic or nucleophilic aromatic substitution reactions.
The synthetic utility of this compound stems largely from the presence of the bromine atom, which serves as an excellent leaving group in various metal-catalyzed cross-coupling reactions. These reactions are cornerstones of modern organic synthesis, enabling the formation of carbon-carbon and carbon-heteroatom bonds with high selectivity and efficiency. For example, Suzuki-Miyaura coupling can be employed to introduce aryl or vinyl groups, while Buchwald-Hartwig amination can be used to form carbon-nitrogen bonds. The synthesis of 4-bromo-2-fluoro-1-(trifluoromethoxy)benzene itself is a testament to advanced organic chemistry techniques.
NINGBO INNO PHARMCHEM CO.,LTD. provides this essential intermediate, offering a reliable source for researchers and manufacturers looking to buy high-quality materials. We ensure that our products, including this fluoro-organic compound, adhere to strict purity standards, which is crucial for the success of complex synthetic routes. The competitive 4-bromo-2-fluoro-1-(trifluoromethoxy)benzene CAS 105529-58-6 price we offer further enhances its accessibility for diverse applications in fine chemical manufacturing.
By providing detailed specifications and consistent product quality, NINGBO INNO PHARMCHEM CO.,LTD. supports the innovation and progress within the chemical industry, enabling chemists to explore new synthetic pathways and develop advanced materials.
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