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The Chemistry of Coagulation: Exploring Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate and Apixaban

The development of effective anticoagulants has revolutionized the treatment of cardiovascular diseases and thrombotic disorders. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying the chemical building blocks essential for these life-saving medications, including compounds like Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate (CAS: 503615-07-4).

This molecule is intrinsically linked to Apixaban, a potent inhibitor of coagulation factor Xa. By targeting factor Xa, Apixaban effectively disrupts the coagulation cascade, preventing the formation of blood clots. This mechanism is crucial for managing conditions like atrial fibrillation and preventing devastating events such as strokes and pulmonary embolisms.

The synthesis of Apixaban is a complex multi-step process, and intermediates like Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate are indispensable. Its specific structure, C22H22N4O4 with a molecular weight of 406.43, provides the foundational scaffold upon which the final Apixaban molecule is constructed. The quality and purity of this intermediate directly influence the quality of the API.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to ensuring that pharmaceutical researchers and manufacturers have access to these critical chemical components. Our role goes beyond simple supply; we are partners in innovation, providing materials that enable advancements in medical treatments. Understanding the chemical properties of compounds such as CAS 503615-07-4 is vital for optimizing synthesis routes and ensuring the consistent production of high-quality pharmaceuticals.

The therapeutic benefits derived from Apixaban, such as the prevention of venous thromboembolism in orthopedic surgery and the management of thromboembolic disorders, are a direct result of sophisticated chemical synthesis and rigorous quality control. Compounds like Ethyl 6-(4-Aminophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate are the silent heroes behind these medical breakthroughs. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to this vital sector.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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