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The Crucial Role of (aR)-4-Chlorophenylglycine Hydrochloride in Modern Drug Development

In the dynamic world of pharmaceutical research and development, the availability of high-quality, precisely structured chemical intermediates is paramount. Among these essential compounds, (aR)-4-Chlorophenylglycine Hydrochloride stands out. This article delves into its significance, applications, and the importance of sourcing it reliably.

The chemical identity of this compound is Benzeneacetic acid, a-amino-4-chloro-, hydrochloride(1:1),( 57187535,aR)-, with the CAS number 108392-76-3. It is characterized by its white powder appearance and an exceptionally high purity level, typically reaching ≥99%. This level of purity is not merely a specification; it is a prerequisite for its use in the intricate processes of Active Pharmaceutical Ingredient (API) synthesis. Impurities, even in trace amounts, can significantly impact the efficacy and safety profile of a final drug product, making the consistent quality of intermediates like this one non-negotiable.

The specific chirality, denoted by '(aR)', is a critical attribute. Chirality refers to the 'handedness' of a molecule, meaning it exists in non-superimposable mirror-image forms. In the pharmaceutical realm, different enantiomers (mirror images) of a drug can exhibit vastly different pharmacological activities, with one enantiomer often being therapeutic while the other might be inactive or even harmful. Therefore, utilizing a stereochemically pure intermediate like (aR)-4-Chlorophenylglycine Hydrochloride is essential for producing enantiomerically pure drugs, thereby maximizing therapeutic benefit and minimizing adverse effects.

The primary application for (aR)-4-Chlorophenylglycine Hydrochloride is as a pharmaceutical intermediate. It serves as a key building block in the multi-step synthesis of various APIs. Its structure, featuring a chlorophenyl group and an amino acid backbone, provides a versatile scaffold for further chemical modifications. This makes it valuable for drug discovery programs targeting a range of therapeutic areas. Pharmaceutical companies and research institutions actively seek reliable suppliers of this compound to ensure uninterrupted progress in their development pipelines.

For those looking to buy alpha-amino-4-chloro-benzeneacetic acid hydrochloride, it is crucial to partner with reputable manufacturers and suppliers. The Chinese fine chemical market offers numerous sources, but quality assurance, timely delivery, and adherence to international standards are key considerations. NINGBO INNO PHARMCHEM CO.,LTD. is a recognized name in the industry, committed to providing high-quality chemical products that meet stringent pharmaceutical requirements. Their expertise in chemical manufacturing ensures that intermediates supplied are consistent in quality and specifications.

The market for such specialized intermediates is driven by the global demand for new and improved pharmaceuticals. As research continues to uncover novel drug targets and therapeutic pathways, the need for complex chiral building blocks like (R)-4-chlorophenylglycine hydrochloride will only grow. Companies that can consistently supply these essential materials will play a pivotal role in advancing healthcare worldwide. The strategic sourcing of these chemicals directly impacts the speed and success of drug development projects, underscoring the importance of selecting knowledgeable and dependable partners in the supply chain.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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