Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight the indispensable role of Povidone K25 (PVP K25) in the pharmaceutical industry. As a synthetic, water-soluble polymer, PVP K25 is renowned for its exceptional versatility, acting as a key excipient that significantly improves drug formulations. Its ability to enhance drug solubility and bioavailability, coupled with its excellent binding and film-forming properties, makes it a cornerstone ingredient in countless medicinal products.
One of the primary functions of PVP K25 is as a binder in tablet manufacturing. It ensures that tablets possess the necessary mechanical strength for production and handling, while also promoting rapid disintegration in the digestive tract for effective drug release. The choice of PVP K25 in tablet formulations, whether through wet granulation or direct compression, guarantees optimal compressibility and flowability of the powders, leading to robust and consistent final products. The specific K-value of K25 (indicating a molecular weight of approximately 30,000-40,000) allows for fine-tuning of viscosity and binding strength, critical for achieving desired tablet characteristics.
Furthermore, PVP K25 excels as a coprecipitating agent, significantly boosting the solubility and dissolution rates of poorly soluble active pharmaceutical ingredients (APIs). This property is crucial for enhancing the therapeutic efficacy and reducing the dosage required for many medications. By inhibiting crystallization and promoting an amorphous state of the drug within the formulation, PVP K25 ensures that the API is readily available for absorption in the body. NINGBO INNO PHARMCHEM CO.,LTD. emphasizes that understanding the optimal PVP K25 to drug ratios is key to maximizing these benefits.
The utility of PVP K25 extends to its function as a stabilizer and dispersant in liquid preparations, including injections and suspensions. It prevents drug precipitation and maintains the homogeneity of the formulation, ensuring accurate dosing and product stability. In ophthalmic solutions, it acts as a lubricant and film-forming agent, enhancing patient comfort and prolonging the residence time of the medication in the eye. The continuous research and development at NINGBO INNO PHARMCHEM CO.,LTD. are focused on leveraging these properties to create next-generation pharmaceutical products.
In essence, Povidone K25 is more than just an inactive ingredient; it is a critical component that actively contributes to the efficacy, safety, and manufacturability of pharmaceutical products. Its broad range of applications underscores its importance in addressing complex formulation challenges and advancing healthcare solutions.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
