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The Crucial Role of TosMIC in Bempedoic Acid Synthesis

NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of high-quality pharmaceutical intermediates. One of our key offerings is (4-Methylphenylsulfonylmethyl) Isocyanide, commonly known as TosMIC, with the CAS number 36635-61-7. This chemical is indispensable in the multi-step synthesis of Bempedoic Acid, a novel non-statin antihyperlipidemic drug that offers a significant advancement in the treatment of hypercholesterolemia.

Bempedoic Acid, developed to help patients manage high cholesterol levels, particularly those who are statin-intolerant, relies on precise chemical synthesis pathways. TosMIC serves as a critical building block in these pathways. Its role in the alkylation and subsequent reactions is fundamental to constructing the complex molecular structure of Bempedoic Acid. The efficient tosmic chemical synthesis is paramount for ensuring the quality and yield of the final Active Pharmaceutical Ingredient (API).

The production of Bempedoic Acid involves transforming ethyl isobutyrate into various intermediates, with TosMIC playing a pivotal role in facilitating key reactions. For instance, the reaction of toluenesulfonyl isocyanide (TosMIC) under basic conditions with an alkyl iodide intermediate is a crucial step that leads to the formation of a new intermediate, which is then processed further to yield Bempedoic Acid. Understanding the bempedoic acid synthesis pathway is essential for appreciating the importance of intermediates like TosMIC.

As a dedicated pharmaceutical intermediate manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. ensures that TosMIC is produced with high purity, typically exceeding 98%. This high purity is critical for subsequent reactions, minimizing by-products and ensuring the efficacy and safety of the final drug product. Our commitment to quality makes us a trusted supplier for companies looking to buy isocyanomethyl 4-methylphenyl sulphone for their pharmaceutical development needs.

The demand for effective lipid-lowering therapies continues to grow, and Bempedoic Acid represents a significant step forward. By providing reliable access to high-quality bempedoic acid intermediate CAS 36635-61-7, NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in supporting the pharmaceutical industry's efforts to develop and distribute life-changing medications. Our expertise in API synthesis building blocks allows us to contribute to the advancement of cardiovascular health globally.

In summary, (4-Methylphenylsulfonylmethyl) Isocyanide is more than just a chemical compound; it is a cornerstone in the production of Bempedoic Acid. Its availability through reliable pharmaceutical intermediate suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that the advancements in cardiovascular medicine can reach the patients who need them most.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
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