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The Essential Role of Barbituric Acid in Pharmaceutical Synthesis

Barbituric acid, with its chemical formula C4H4N2O3 and CAS number 67-52-7, stands as a cornerstone organic intermediate, particularly vital within the pharmaceutical industry. As a parent compound for barbiturate drugs, its synthesis and availability are of paramount importance to researchers and manufacturers alike. This white to cream-colored crystalline powder, characterized by its odorless nature and solubility in water, possesses a unique chemical structure that makes it a versatile building block for a wide array of complex organic molecules.

The synthesis of Barbituric acid typically involves the condensation of diethyl malonate with urea. This process, while established, requires precise control to ensure the high purity (often ≥99.0%) demanded by pharmaceutical applications. Sourcing high-quality barbituric acid from reputable manufacturers, especially those based in China, can offer significant cost advantages without compromising on quality. For procurement managers and R&D scientists, understanding the nuances of sourcing, including supplier reliability and competitive pricing, is key to efficient operations. When looking to buy barbituric acid, it's crucial to consider suppliers who can provide detailed specifications, certificates of analysis, and consistent supply.

Beyond its role as a precursor to sedative and hypnotic drugs, barbituric acid itself finds application in the synthesis of Vitamin B2 and serves as a valuable intermediate for plastics and dye manufacturing. Its reactive methylene group also makes it amenable to Knoevenagel condensation, a fundamental reaction in organic synthesis for creating more complex derivatives. For those in the chemical industry, whether you are looking for barbituric acid for organic synthesis, as a pharmaceutical intermediate, or for other industrial uses, identifying a dependable manufacturer is the first step towards successful product development and commercialization. Explore pricing and supplier options from leading Chinese chemical producers to secure this essential compound for your R&D or production needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
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