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The Essential Role of Ethyl 7-chloro-2-oxoheptanoate in Pharmaceutical Synthesis

Ethyl 7-chloro-2-oxoheptanoate, identified by its CAS number 78834-75-0, stands as a cornerstone compound in the contemporary pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. recognizes its profound importance, particularly in the synthesis of critical therapeutic agents. This alpha-keto ester is indispensable for the production of cilastatin, a dehydropeptidase inhibitor that plays a vital role in prolonging the efficacy of antibiotics such as imipenem. By preventing the enzymatic degradation of imipenem, cilastatin ensures that the antibiotic remains active in the body for a longer duration, thereby improving treatment outcomes for severe bacterial infections.

The synthesis of cilastatin often involves the reaction of Ethyl 7-chloro-2-oxoheptanoate with specific chiral intermediates, showcasing the precision required in pharmaceutical manufacturing. Beyond its primary use, the versatile nature of Ethyl 7-chloro-2-oxoheptanoate extends to its utility as an organic synthesis reagent. Researchers and manufacturers utilize its reactive functional groups to construct more complex molecular architectures, contributing to the development of novel drug candidates targeting a range of diseases. The ability to buy Ethyl 7-chloro-2-oxoheptanoate online from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. facilitates smoother research and production workflows.

Understanding the chemical properties of Ethyl 7-chloro-2-oxoheptanoate is paramount for its effective application. Typically appearing as a light yellow liquid with a high purity standard of 99% or more, it is soluble in common organic solvents like acetonitrile and ethyl acetate. Its stability is best maintained when stored under an inert atmosphere at refrigerated temperatures (2-8°C). The pricing for this crucial chemical intermediate can vary, but securing a consistent supply is key for companies involved in antibiotic formulation and drug discovery. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Ethyl 7-chloro-2-oxoheptanoate to support these vital industries, ensuring a steady supply for both research quantities and bulk purchase needs. As the demand for effective treatments grows, the significance of this pharmaceutical intermediate chemical continues to rise.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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