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The Essential Role of PVP K30 in Pharmaceutical Formulations

NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight the indispensable role of Povidone K30 (PVP K30) within the pharmaceutical industry. This versatile, water-soluble polymer, scientifically known as polyvinylpyrrolidone, has become a cornerstone excipient due to its remarkable range of functionalities. From enhancing drug dissolution to acting as a robust tablet binder, PVP K30 significantly contributes to the efficacy and stability of various medicinal products.

One of the primary benefits of utilizing PVP K30 in pharmaceutical formulations is its exceptional capability as a dissolution enhancer. For many active pharmaceutical ingredients (APIs) that suffer from poor water solubility, PVP K30 can dramatically improve their dissolution rates. This is achieved through its ability to form amorphous solid dispersions or complexes with the API, thereby increasing its apparent solubility and improving its bioavailability. This directly translates to more effective drug delivery and potentially lower required dosages.

Furthermore, the efficacy of PVP K30 as a tablet binder is well-established. When used in tablet manufacturing, whether through wet granulation, dry granulation, or direct compression methods, it imparts excellent binding properties. This ensures that tablets are robust, non-friable, and maintain their integrity throughout production, packaging, and patient use. The consistent quality of the tablets is paramount, and PVP K30 consistently delivers reliable binding performance.

Beyond its roles in dissolution and binding, PVP K30 also functions effectively as a suspending agent. In liquid formulations, it helps to keep insoluble particles uniformly dispersed, preventing sedimentation and ensuring dose consistency. This is particularly important for suspensions and liquid dosage forms where particle settling could lead to inaccurate dosing and reduced therapeutic effect. The application of povidone K30 as a pharmaceutical excipient is broad, covering oral solids, injectables, and topical preparations.

The accessibility and affordability of PVP K30, coupled with its proven safety profile and regulatory approvals (including USP, BP, EP, CP), make it a preferred choice for many drug manufacturers. Understanding the povidone K30 chemical properties and its various applications is crucial for any pharmaceutical company aiming to develop high-quality, effective, and stable drug products. For those seeking reliable sources and expert guidance on utilizing this vital ingredient, NINGBO INNO PHARMCHEM CO.,LTD. offers extensive support and high-quality product supply to meet your formulation needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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