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The pharmaceutical industry is in constant pursuit of innovation, driving the demand for high-quality chemical intermediates that form the backbone of modern drug development and manufacturing. 1-Acetylpiperazine, bearing the CAS number 13889-98-0, is one such indispensable compound. Its unique chemical structure and properties make it a vital component in the synthesis of a wide range of therapeutic agents. For pharmaceutical companies and contract manufacturers, understanding the applications and ensuring a stable supply of this intermediate is paramount.
1-Acetylpiperazine: A Versatile Pharmaceutical Intermediate
With the molecular formula C6H12N2O and a molecular weight of 128.17, 1-Acetylpiperazine is a derivative of piperazine, a six-membered heterocyclic ring containing two nitrogen atoms. This structure provides a versatile scaffold for medicinal chemists. The acetyl group attached to one of the nitrogen atoms influences its reactivity and allows for further functionalization. Typically supplied at a minimum purity of 97%, its physical form is often described as a pale yellow crystal, with a melting point around 31-34 °C. These characteristics make it manageable for standard chemical synthesis processes within the pharmaceutical sector.
Applications in Drug Synthesis
The primary significance of 1-Acetylpiperazine lies in its role as a key intermediate in the synthesis of various Active Pharmaceutical Ingredients (APIs). It can be incorporated into molecules targeting a broad spectrum of conditions, including but not limited to:
Its presence in a synthetic route can be crucial for achieving the desired pharmacological profile of a drug candidate. Therefore, sourcing high-purity 1-Acetylpiperazine is critical for ensuring the efficacy, safety, and regulatory compliance of the final pharmaceutical product. When looking to buy 1-Acetylpiperazine, pharmaceutical manufacturers must prioritize suppliers who can demonstrate consistent quality and adhere to stringent manufacturing standards.
Ensuring Quality and Supply Chain Reliability
The pharmaceutical industry operates under rigorous regulatory scrutiny. This extends to the sourcing of raw materials and intermediates. For companies seeking to purchase 1-Acetylpiperazine, partnering with reliable manufacturers and suppliers is essential. Key considerations include:
Manufacturers in China have become a significant source for these intermediates. When engaging with them, focusing on those with a proven track record in pharmaceutical-grade materials is advisable. Understanding the price and lead times associated with bulk orders of 1-Acetylpiperazine will allow for effective production planning.
Conclusion
1-Acetylpiperazine (CAS 13889-98-0) is more than just a chemical compound; it is a foundational element in the development of life-saving and life-enhancing medications. Its reliable and high-quality supply, sourced from reputable suppliers, is a critical component of successful pharmaceutical manufacturing. As the industry continues to evolve, the demand for such foundational intermediates will only grow, underscoring the importance of strategic sourcing partnerships.
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A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
