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In the realm of pharmaceutical chemistry, specialized molecules like (3R,4S)-Tofacitinib (CAS 1092578-46-5) play a critical role. This compound, with its precise stereochemistry and molecular structure, is not just another chemical; it is an enabler of complex synthetic pathways and a vital tool for ensuring drug quality. Understanding its applications is key for researchers and procurement specialists looking to buy this compound.
What is (3R,4S)-Tofacitinib?
(3R,4S)-Tofacitinib is a specific stereoisomer with the chemical formula C16H20N6O and a molecular weight of 312.37. Its distinct configuration makes it a valuable pharmaceutical intermediate. Often identified by its CAS number 1092578-46-5, it is recognized for its role in research and development, particularly in areas involving kinase inhibition.
Applications in Pharmaceutical Synthesis
The primary use of (3R,4S)-Tofacitinib lies in its function as a pharmaceutical intermediate. It serves as a chiral building block in the synthesis of more complex active pharmaceutical ingredients (APIs). The specific stereochemistry of (3R,4S)-Tofacitinib is often essential for the biological activity and safety profile of the final drug product. Pharmaceutical companies rely on manufacturers who can provide this compound with high purity (typically 98%) to ensure successful and reproducible synthesis runs.
Role as an Impurity Standard
Beyond its role in synthesis, (3R,4S)-Tofacitinib can also function as an important impurity standard. During the development and manufacturing of related pharmaceutical compounds, identifying and quantifying potential impurities is critical for regulatory compliance. As a defined stereoisomer, (3R,4S)-Tofacitinib can be used to develop analytical methods to detect and measure its presence as an impurity, thereby ensuring the quality and safety of the final drug product.
Research Chemical Applications
For academic institutions and contract research organizations (CROs), (3R,4S)-Tofacitinib is a valuable research chemical. It allows scientists to explore new synthetic routes, investigate pharmacological mechanisms, and develop novel therapeutic agents. The availability of this compound from reliable (3R,4S)-Tofacitinib suppliers, often with comprehensive documentation, supports the advancement of scientific discovery.
Sourcing and Procurement Considerations
When looking to purchase (3R,4S)-Tofacitinib, prospective buyers should focus on suppliers who offer:
By prioritizing these factors, researchers and procurement managers can secure a trusted source for (3R,4S)-Tofacitinib, enabling them to drive their projects forward with confidence. As a dedicated manufacturer, we are committed to providing the high-quality chemical solutions needed by the global pharmaceutical industry.
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
