Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
Antibody-Drug Conjugates (ADCs) represent a significant advancement in targeted cancer therapy. At their core, ADCs are sophisticated molecules that combine the specificity of monoclonal antibodies with the potent cytotoxic power of small molecule drugs. This innovative approach aims to deliver highly toxic agents directly to cancer cells, minimizing damage to healthy tissues. As a leading manufacturer and supplier of these vital components, we understand the critical importance of high-quality cytotoxic payloads.
The cytotoxic payload is the 'warhead' of the ADC, responsible for killing cancer cells. These payloads are often extremely potent compounds that would be too toxic for systemic administration on their own. By conjugating them to a tumor-targeting antibody, their activity is localized, drastically improving the therapeutic index. Mertansine (CAS 139504-50-0), chemically known as N2'-deacetyl-N2'-(3-Mercapto-1-oxopropyl)-Maytansine, is a prime example of such a payload. Its mechanism of action involves inhibiting microtubule polymerization, leading to cell cycle arrest and apoptosis in rapidly dividing cancer cells.
The production of these highly potent cytotoxic agents requires specialized expertise and stringent quality control. As a reliable manufacturer and supplier based in China, we are committed to providing N2'-deacetyl-N2'-(3-Mercapto-1-oxopropyl)-Maytansine with exceptional purity (98%). This ensures that our clients, ranging from research institutions to pharmaceutical companies, can confidently incorporate it into their ADC development pipelines. The ability to buy such critical intermediates at a competitive price is crucial for accelerating drug discovery and bringing new therapies to market.
The supply chain for pharmaceutical intermediates is complex, and securing a consistent and reliable source for potent cytotoxic agents is paramount. We pride ourselves on our robust manufacturing capabilities and efficient logistics, ensuring that our customers receive their orders promptly, whether they need small research quantities or bulk for commercial production. Our goal is to be your trusted partner in the supply of essential ADC components, facilitating breakthroughs in oncology.
If you are engaged in ADC research and development, understanding the sourcing of your cytotoxic payloads is key. We invite you to inquire about our N2'-deacetyl-N2'-(3-Mercapto-1-oxopropyl)-Maytansine. Contact us today to request a quote or discuss your specific requirements. Partner with a dedicated manufacturer and supplier to advance your therapeutic innovations.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
