All-Trans-Retinal (CAS 116-31-4), also known as Vitamin A aldehyde, is a molecule of profound scientific importance. Its name itself hints at its fundamental role in vision, but its influence extends into other biological processes and research avenues. For scientists and researchers, understanding its properties and sourcing reliable quantities is key to unlocking further discoveries.

The most well-documented function of All-Trans-Retinal is its central role in the vertebrate visual cycle. Within the photoreceptor cells of the retina, it acts as the light-sensitive chromophore. When light strikes rhodopsin (or other visual pigments), All-Trans-Retinal undergoes a rapid isomerization to its 11-cis form. This geometric change is the critical first step in a biochemical cascade that ultimately leads to the transmission of a visual signal to the brain. The ability of All-Trans-Retinal to absorb photons and trigger this isomerization is the fundamental basis of sight as we know it. Researchers in ophthalmology and molecular biology frequently require high-purity All-Trans-Retinal for studies into the visual process, retinal diseases, and the development of vision-restoring therapies.

Beyond vision, All-Trans-Retinal's connection to Vitamin A makes it relevant to a broader spectrum of biological research. Vitamin A and its various forms, including retinol, retinal, and retinoic acid, are essential for numerous physiological functions, such as cell growth, differentiation, and immune response. All-Trans-Retinal serves as a key intermediate in the metabolism of these retinoids, making it valuable for studies investigating retinoid signaling pathways and their impact on health and disease. The precise chemical synthesis and characterization of compounds like All-Trans-Retinal are therefore critical for accurate scientific investigation.

For laboratories and research institutions, sourcing All-Trans-Retinal requires adherence to strict quality standards. Purity is paramount, as even trace impurities can significantly impact experimental results. Reputable manufacturers, such as those in China specializing in fine chemicals, offer All-Trans-Retinal with guaranteed high assay percentages (typically ≥98%). These suppliers provide the necessary documentation, including Certificates of Analysis, to verify the product's quality and suitability for demanding scientific applications. Understanding the typical price for All-Trans-Retinal per gram or kilogram is also essential for research budget planning.

The availability of All-Trans-Retinal as a yellow powder allows for straightforward integration into various experimental protocols, though appropriate storage conditions (typically at -20°C and protected from light) are necessary to maintain its stability. For any scientist or procurement specialist seeking this vital compound, partnering with an experienced and reliable supplier ensures the integrity of their research and the advancement of scientific knowledge.