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Anagrelide hydrochloride, identified by CAS number 58579-51-4, stands as a significant pharmaceutical compound primarily recognized for its efficacy in treating essential thrombocythemia. This condition is characterized by an overproduction of blood platelets, which can lead to serious health risks. Anagrelide hydrochloride works by targeting and inhibiting phosphodiesterase type III (PDE3), a crucial enzyme in cellular signaling pathways that regulate platelet production. By inhibiting PDE3, anagrelide hydrochloride effectively disrupts the maturation process of megakaryocytes, the precursor cells responsible for generating platelets. This targeted approach helps to normalize platelet counts, thereby mitigating the thrombotic risks associated with essential thrombocythemia.
The anagrelide hydrochloride mechanism of action is multifaceted. Beyond its direct impact on megakaryocyte maturation, it also influences platelet aggregation. Studies indicate that anagrelide hydrochloride can reduce the responsiveness of platelets to various aggregating agents, further contributing to its therapeutic benefits. This makes it an invaluable tool for researchers investigating platelet function and the complex processes involved in hemostasis and thrombosis. For those seeking to buy anagrelide hydrochloride online for research purposes, ensuring a reliable source for high-purity material is paramount.
The significance of anagrelide hydrochloride extends into its role as a vital anagrelide hydrochloride pharmaceutical intermediate. Its availability in high purity, often exceeding 99% via HPLC, makes it suitable for use in the synthesis of active pharmaceutical ingredients (APIs) and in advanced drug discovery programs. Pharmaceutical companies and research institutions rely on such high-quality intermediates to develop new therapeutic agents or to ensure the consistent production of existing medications. The demand for anagrelide hydrochloride is driven by its proven clinical utility and its ongoing exploration in various research contexts, from understanding cardiovascular disease mechanisms to developing novel treatments for myeloproliferative neoplasms.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying high-quality chemical products to the global market. Our extensive catalog includes essential compounds like anagrelide hydrochloride, crucial for advancements in medical research and pharmaceutical manufacturing. We understand the critical need for reliable and pure chemical intermediates, and we strive to be a trusted partner for scientists and manufacturers worldwide. Exploring the therapeutic potential and research applications of compounds like anagrelide hydrochloride is central to our mission, contributing to better health outcomes and scientific discovery.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
