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The Science Behind Effective Cancer Drugs: Focusing on 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic Acid

The intricate science behind modern pharmaceutical development relies heavily on the availability of high-quality chemical intermediates. Among these, 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid has emerged as a critical component, especially in the synthesis of powerful anticancer drugs like Olaparib. As a leading pharmaceutical intermediate supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to producing this compound with exceptional purity and consistency, thereby supporting the advancement of cancer therapies worldwide.

2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid is central to the creation of molecules that target specific biological pathways essential for cancer cell survival. Its most notable application is as a key intermediate in the manufacturing of Olaparib, a groundbreaking PARP inhibitor. PARP enzymes are critical for repairing DNA damage within cells. By inhibiting these enzymes, especially in cancer cells that already have compromised DNA repair mechanisms, treatment can lead to an accumulation of DNA damage, triggering programmed cell death (apoptosis). This targeted approach is significantly improving treatment outcomes for various cancers.

NINGBO INNO PHARMCHEM CO.,LTD. excels in the precise chemical synthesis of this important intermediate. Our commitment to quality means that the 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid we supply typically boasts a purity of ≥98%, alongside strict controls on impurities. This adherence to high standards is crucial for pharmaceutical applications, ensuring the safety and efficacy of the final drug product. As a reliable pharmaceutical intermediate supplier in China, we understand the critical nature of these materials in the drug development pipeline and strive to maintain consistent supply and quality.

The chemical structure of 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid, characterized by its molecular formula C16H11FN2O3 and a molecular weight of approximately 298.27, makes it an ideal precursor for creating sophisticated drug molecules. Its utility is not limited to Olaparib; it also serves as a versatile building block for research into new generations of targeted therapies and compounds with potential anticancer activity, such as isocorydine derivatives. This broad applicability underscores its value in ongoing pharmaceutical research and development.

In conclusion, NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in the pharmaceutical supply chain by providing high-quality 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid. Our expertise in chemical synthesis, coupled with a steadfast commitment to quality, enables researchers and manufacturers to develop and produce the advanced cancer treatments that patients urgently need. We are proud to be a key enabler of innovation in the fight against cancer.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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