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The Science Behind MCC: Understanding Its Physicochemical Properties for Pharmaceutical Success

Microcrystalline Cellulose (MCC) is more than just a filler; it's a scientifically engineered material whose physicochemical properties are the bedrock of its widespread use in pharmaceutical formulations. At NINGBO INNO PHARMCHEM CO.,LTD., we understand that a deep appreciation of these properties is vital for formulators aiming for optimal drug delivery and manufacturing efficiency. MCC's journey from refined wood pulp to a pharmaceutical grade excipient involves precise processing that imbues it with remarkable characteristics.

The defining feature of MCC is its crystalline structure, formed by the controlled acid hydrolysis of cellulose. This process removes amorphous regions, leaving behind highly ordered crystallites. This structure imparts excellent compressibility, allowing MCC particles to deform plastically under pressure and create strong inter-particle bonds. This is why MCC is renowned as a powerful binder, essential for tablet integrity. Its ability to form robust compacts is a critical factor when purchasing MCC for tablet production.

Furthermore, MCC's porous nature is key to its function as a disintegrant. Upon contact with water, these pores readily absorb moisture, causing the MCC particles to swell. This swelling action disrupts the tablet matrix, facilitating rapid disintegration and ensuring the timely release of the active pharmaceutical ingredient. This efficient disintegration directly impacts drug absorption and therapeutic efficacy, making it a sought-after quality in pharmaceutical excipients.

The flowability of MCC is another significant property. As a free-flowing powder, it ensures consistent die filling during tableting, contributing to uniform tablet weight and content uniformity – critical parameters for quality control. This characteristic simplifies manufacturing processes, especially in high-speed tablet presses. NINGBO INNO PHARMCHEM CO.,LTD. ensures that the MCC supplied possesses optimal flow properties to support these manufacturing demands.

The chemical inertness of MCC is also paramount. It does not react with most APIs, safeguarding the stability and efficacy of the final drug product throughout its shelf life. This lack of reactivity makes it a safe and reliable choice for a broad spectrum of medications. Understanding these physicochemical properties – its crystalline structure, porosity, flowability, and inertness – is essential for formulators who want to buy MCC and unlock its full potential in creating advanced and effective pharmaceutical products.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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