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NINGBO INNO PHARMCHEM CO.,LTD. provides valuable insights into the scientific underpinnings of Povidone K25 (PVP K25), a synthetic polymer that has become a critical component in numerous industries. Understanding its chemical properties, manufacturing process, and quality control measures is essential for appreciating its consistent performance as a pharmaceutical excipient and cosmetic ingredient.
PVP K25 is a homopolymer of N-vinylpyrrolidone, characterized by a K-value range of 22.5-27.0, which corresponds to a specific average molecular weight (approximately 30,000-40,000 g/mol). This molecular characteristic dictates its viscosity and solubility, differentiating it from other PVP grades like K15 or K90. Its white to off-white powder form is readily soluble in water and a variety of organic solvents, including alcohols and chlorinated hydrocarbons, yet insoluble in acetone and ether. This selective solubility is a key attribute for its diverse applications.
The manufacturing of PVP K25 typically involves the free-radical polymerization of N-vinylpyrrolidone. This process requires careful control of reaction conditions, initiators, and catalysts to achieve the desired molecular weight and purity. NINGBO INNO PHARMCHEM CO.,LTD. employs stringent manufacturing protocols to ensure that its PVP K25 meets high standards for chemical purity, low peroxide levels, and consistent physical characteristics. Adherence to Good Manufacturing Practices (GMP) is paramount for pharmaceutical-grade excipients.
Quality control is a critical aspect of PVP K25 production. Rigorous testing is conducted to verify parameters such as appearance, solubility, K-value, pH, water content, residue on ignition, heavy metals, and impurities like vinylpyrrolidone monomer and aldehydes. Certifications such as USP, EP, BP, JP, CP, GMP, CEP, DMF, Kosher, and Halal are indicative of the stringent quality assurance processes undertaken by reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD.
The stability of PVP K25 is also noteworthy. While hygroscopic and requiring proper storage in airtight containers, it is generally stable under normal conditions. Its biocompatibility and low toxicity profile further enhance its appeal as a safe and effective excipient. NINGBO INNO PHARMCHEM CO.,LTD. is committed to transparency in its product specifications and quality documentation, empowering formulators to confidently integrate PVP K25 into their products.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
