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Understanding the science behind pharmaceutical excipients is key to unlocking their full potential. Povidone PVP K90 (CAS: 9003-39-8), a versatile water-soluble polymer, plays a crucial role in modern drug formulation. Ningbo Inno Pharmchem Co., Ltd., a leading provider of chemical materials, offers insights into the synthesis, properties, and applications that make Povidone PVP K90 an indispensable ingredient.
The synthesis of Povidone involves the polymerization of N-vinylpyrrolidone. This process, carefully controlled by manufacturers like Ningbo Inno Pharmchem Co., Ltd., results in polymers with varying molecular weights, denoted by the K-value. The K90 grade signifies a higher molecular weight, which translates to specific rheological properties and enhanced binding capabilities. These characteristics are fundamental to its use as a povidone binder for tablets, providing the necessary adhesion for tablet integrity.
Scientifically, Povidone PVP K90 is valued for its amphiphilic nature and its ability to interact with a wide range of molecules through hydrogen bonding and Van der Waals forces. This enables it to function effectively in improving drug solubility with PVP, creating stable dispersions that enhance the bioavailability of poorly soluble active pharmaceutical ingredients (APIs). The mechanism involves complexation, where the drug molecules are entrapped within the polymer matrix, preventing crystallization and promoting dissolution.
The polymer's water solubility also makes it an excellent choice as a polyvinylpyrrolidone oral liquid stabilizer. In liquid formulations, it helps to maintain uniformity, prevent phase separation, and control viscosity, ensuring consistent product quality and patient adherence. Ningbo Inno Pharmchem Co., Ltd. ensures that their pharmaceutical grade povidone K90 meets the purity and consistency required for these applications.
For those looking to buy povidone K90 online, understanding its scientific basis is crucial for informed purchasing. The polymer's inherent safety profile, coupled with its functional versatility, makes it a cornerstone excipient. Whether it's for tablet binding, solubility enhancement, or stabilization of liquid formulations, the science behind Povidone PVP K90 supports its widespread adoption in the pharmaceutical industry.
Ningbo Inno Pharmchem Co., Ltd. is committed to advancing pharmaceutical science by providing high-quality Povidone PVP K90 and related technical expertise. Their dedication as a povidone K90 manufacturer ensures that researchers and formulators have access to the materials needed to develop the next generation of effective and safe medicines.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
