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The Science of PVP K15: Properties and Mechanisms in Diverse Applications

Povidone K15 (PVP K15), a prominent member of the polyvinylpyrrolidone family, owes its remarkable efficacy across pharmaceutical, cosmetic, and industrial sectors to its unique polymer structure and physical-chemical properties. At NINGBO INNO PHARMCHEM CO.,LTD., we delve into the scientific principles that make PVP K15 such a valuable compound.

The fundamental structure of PVP K15 is a homopolymer of N-vinylpyrrolidone, characterized by a pyrrolidone ring within its repeating units. This polar lactam ring is responsible for PVP K15's excellent water solubility and its ability to interact with a wide range of substances through hydrogen bonding and complex formation. The K-value, specifically for K15, indicates a moderate molecular weight (around 8,000-12,000 Da), which strikes a balance between solubility, viscosity, and film-forming properties.

In pharmaceutical applications, PVP K15 functions as a binder by forming strong hydrogen bonds with drug particles and excipients, creating robust granules and tablets. As a dispersant, its polar nature allows it to adsorb onto solid particles, preventing agglomeration and maintaining uniform suspension in liquid formulations. Its role as a solubilizer for poorly soluble drugs involves complexation, where the drug molecules are entrapped within the polymer matrix, thereby increasing their apparent solubility.

In cosmetics, the film-forming ability of PVP K15 is attributed to the polymer chains aligning and coalescing upon drying, creating a flexible, transparent film on surfaces like hair or skin. This film provides hold in hair styling products and can also contribute to the texture and feel of skincare formulations. Its stabilizing action in emulsions and dispersions prevents phase separation, ensuring product integrity.

Industrially, PVP K15's capacity to form complexes with dyes makes it an excellent dye dispersant in textiles and inks. Its adhesive properties arise from intermolecular forces that promote adhesion to various surfaces. The versatility of PVP K15 stems from this intricate interplay of its chemical structure, molecular weight, and polarity, enabling it to perform multiple functions effectively. For those looking to buy PVP K15, understanding these scientific mechanisms helps in optimizing its application for superior results.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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