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The Strategic Role of Piperazine Derivatives in Modern Drug Discovery

In the dynamic landscape of pharmaceutical research and development, the strategic utilization of specialized chemical intermediates plays a pivotal role. Among these, piperazine derivatives stand out for their versatile applications and significant contributions to drug discovery. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying high-quality compounds that enable advancements in various therapeutic areas.

One such critical compound is 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride (CAS: 70918-74-0). This compound is widely recognized for its utility as a key intermediate in the synthesis of Doxazosin, a widely prescribed alpha-1 blocker used to treat hypertension and benign prostatic hyperplasia. The efficient pharmaceutical intermediate synthesis of such vital drugs relies heavily on the availability of pure and well-characterized building blocks.

The importance of compounds like this cannot be overstated. They are the fundamental units from which complex drug molecules are assembled. Researchers often seek these specialized molecules when exploring novel chemical entities for various medical conditions. The precise structure and reactivity of these intermediates, such as those found in piperazine derivative synthesis, allow medicinal chemists to construct molecules with desired pharmacological profiles.

The application of these intermediates extends beyond a single drug. Many piperazine-containing compounds exhibit significant biological activity, targeting a wide range of receptors and enzymes. This makes them valuable in the development of treatments for central nervous system disorders, infectious diseases, and oncology, among others. The ability to modify the piperazine ring and its substituents allows for fine-tuning of pharmacokinetic and pharmacodynamic properties.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the pharmaceutical industry by providing reliable access to these essential building blocks. Our dedication to quality ensures that every batch meets stringent purity standards, facilitating reproducible and successful research outcomes. Whether you are engaged in early-stage drug discovery or optimizing established synthesis pathways, our portfolio is designed to meet your needs.

For those interested in the specifics of synthesizing potent drugs like Doxazosin, understanding the role of intermediates like 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride is crucial. Exploring the intricacies of organic synthesis and the selection of appropriate reagents is fundamental to achieving desired therapeutic agents.

In essence, the journey from a chemical intermediate to a life-saving medication is a testament to the power of chemistry and innovation. NINGBO INNO PHARMCHEM CO.,LTD. proudly contributes to this process by supplying the foundational chemical compounds that drive progress in healthcare.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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