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The fight against malaria has long relied on effective combination therapies, and the pairing of Sulfadoxine with Pyrimethamine stands as a prime example of synergistic antimicrobial action. NINGBO INNO PHARMCHEM CO.,LTD. delves into the scientific basis and pharmaceutical significance of this powerful combination.
Sulfadoxine, a long-acting sulfonamide, and Pyrimethamine, a dihydrofolate reductase inhibitor, work sequentially to disrupt the folic acid synthesis pathway in the malaria parasite, Plasmodium falciparum. Sulfadoxine inhibits an earlier step in the pathway, while Pyrimethamine targets a later enzymatic step. This sequential blockade prevents the parasite from synthesizing essential nucleic acids and amino acids, leading to its death. Understanding this sulfadoxine antibiotic mechanism of action, in conjunction with Pyrimethamine, underscores the critical need for high-quality components.
For pharmaceutical manufacturers, sourcing both sulfadoxine raw material for sale and Pyrimethamine requires strict adherence to quality standards. The sulfadoxine powder purity and the purity of Pyrimethamine are paramount to ensure the therapeutic efficacy and safety of combination drugs. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated sulfadoxine supplier China, providing reliably pure Sulfadoxine to meet these demands.
The historical effectiveness of this combination therapy has cemented its place in malaria treatment protocols. While resistance patterns evolve, the fundamental principle of synergy remains a powerful strategy in combating infectious diseases. Ensuring a consistent supply of the necessary APIs, like Sulfadoxine (CAS 2447-57-6), is vital for public health initiatives worldwide.
By choosing to buy Sulfadoxine pharmaceutical grade from trusted sources, manufacturers can guarantee the quality and reliability of their antimalarial medications. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting global health efforts by providing essential, high-purity pharmaceutical raw materials like Sulfadoxine.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
