Ethyl Trifluoroacetate (CAS 383-63-1) is a compound that plays a remarkably versatile role in modern chemical synthesis. As a colorless, transparent liquid, its chemical structure (C4H5F3O2) and physical properties—including a boiling point of 61.5±3.0 °C and a flash point of -1.1±0.0 °C—make it a highly adaptable reagent. Its significance is most pronounced in the pharmaceutical industry, where it serves as a key intermediate in the production of Celecoxib, a prominent NSAID. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated ethyl trifluoroacetate manufacturer and supplier in China, facilitates these crucial synthesis pathways.
The primary application of Ethyl Trifluoroacetate is its function as an intermediate in the synthesis of Celecoxib. The introduction of the trifluoroacetyl group is essential for achieving the drug's desired pharmacological profile, contributing to its efficacy and stability. This specific role highlights the compound's importance in creating complex pharmaceutical molecules. For businesses looking to buy ethyl trifluoroacetate for these purposes, understanding its properties and reliable sourcing options is vital. Our company ensures that we provide ethyl trifluoroacetate with an assay of ≥98.0% by GC, meeting the high purity standards required by the pharmaceutical sector.
Beyond its application in Celecoxib synthesis, Ethyl Trifluoroacetate is highly valued for its ability to introduce fluorine atoms into organic molecules. This process, known as fluorination, can significantly alter a compound's characteristics, such as increasing its lipophilicity, enhancing its metabolic stability, and improving its overall bioactivity. These attributes are highly desirable in the development of new drugs and agrochemicals. Consequently, Ethyl Trifluoroacetate is a key component in custom synthesis celecoxib intermediates and other specialized chemical projects that aim to leverage the unique benefits of fluorination.
The accessibility and cost-effectiveness of sourcing chemicals from China have made it a global hub for chemical manufacturing. NINGBO INNO PHARMCHEM CO.,LTD. leverages this advantage to offer reliable access to Ethyl Trifluoroacetate. Our commitment extends beyond just manufacturing; we aim to be a comprehensive ethyl trifluoroacetate supplier, providing consistent quality and dependable delivery. Whether for research and development or large-scale production, our facilities are equipped to meet diverse client needs, including customized packaging solutions.
In summary, the versatile applications of Ethyl Trifluoroacetate in chemical synthesis underscore its importance in modern industrial processes. From its foundational role in pharmaceutical production to its broader use in creating advanced fluorinated compounds, this chemical precursor is indispensable. Partnering with an experienced ethyl trifluoroacetate producer in China like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to high-quality material and expert support, facilitating innovation and efficiency in chemical synthesis.
Manufacturing Facilities






Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.